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Na/K-Atpase Amplification Of Oxidant Stress; A Universal But Unrecognized Clinical Target?, Joseph I. Shapiro Md Apr 2016

Na/K-Atpase Amplification Of Oxidant Stress; A Universal But Unrecognized Clinical Target?, Joseph I. Shapiro Md

Joseph I Shapiro MD

Schematic showing Na/K‐ATPase as reactive oxygen species (ROS) amplifier system. CTS‐cardiotonic steroids, Orange dimer is Na/K‐ATPase. pNaKtide refers to peptide formed from epitope of Na/K‐ATPase a1 subunit known to bind Src tyrosine kinase fused with TAT leader sequence.

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