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Articles 31 - 60 of 231
Full-Text Articles in Life Sciences
Shingles, Pratibha Bhalla '20, Zahra Vasi '20, Shivang Bhaskar '20, Sophia Pribus '20
Shingles, Pratibha Bhalla '20, Zahra Vasi '20, Shivang Bhaskar '20, Sophia Pribus '20
Human Diseases Graphic Novels
No abstract provided.
Diabetes, Kailey A. Light '21, Tori Shepherd '21, Jemea Hilmara '20
Diabetes, Kailey A. Light '21, Tori Shepherd '21, Jemea Hilmara '20
Human Diseases Graphic Novels
No abstract provided.
Invasion Of The Pollen, Elizabeth Murphy '20, Rachel Mason '20, Jodie Meng '20, Shouri Bochetty '21
Invasion Of The Pollen, Elizabeth Murphy '20, Rachel Mason '20, Jodie Meng '20, Shouri Bochetty '21
Human Diseases Graphic Novels
No abstract provided.
Effect Of N-Acetyl-L-Cysteine Prevention Or Intervention On Diet Induced Beta Cell Compensation And Dysfunction, Madison Wallace
Effect Of N-Acetyl-L-Cysteine Prevention Or Intervention On Diet Induced Beta Cell Compensation And Dysfunction, Madison Wallace
Electronic Thesis and Dissertation Repository
Type 2 diabetes mellitus (T2DM) progression increases oxidative stress which contributes to beta cell compensation and eventual dysfunction. To investigate the role of antioxidant N-acetyl-L-cysteine (NAC) on beta cell function and pancreatic stellate cell activation (aSMA+) during early and late stages of compensation, NAC was used for preventative (p) and intervention (i) treatments in C57BL/6N mice fed a 60% kcal high-fat diet (HFD) for 8 or 22 weeks. Significantly improved glucose tolerance was observed at 22 weeks following pNAC treatment in HFD mice. Although 22-week HFD mice displayed hyperinsulinemia, beta cell hypertrophy, decreased beta cell PDX-1 nuclear localization, …
In Search Of Psychiatric Kinds: Natural Kinds And Natural Classification In Psychiatry, Nicholas Slothouber
In Search Of Psychiatric Kinds: Natural Kinds And Natural Classification In Psychiatry, Nicholas Slothouber
Electronic Thesis and Dissertation Repository
In recent years both philosophers and scientists have asked whether or not our current kinds of mental disorder—e.g., schizophrenia, depression, bipolar disorder—are natural kinds; and, moreover, whether or not the search for natural kinds of mental disorder is a realistic desideratum for psychiatry. In this dissertation I clarify the sense in which a kind can be said to be “natural” or “real” and argue that, despite a few notable exceptions, kinds of mental disorder cannot be considered natural kinds. Furthermore, I contend that psychopathological phenomena do not cluster together into kinds in the way that paradigmatic natural kinds (e.g., chemical …
Transient Dynamics Of Infection Transmission In An Intensive Care Unit, Christopher Short, Matthew S. Mietchen, Eric T. Lofgren
Transient Dynamics Of Infection Transmission In An Intensive Care Unit, Christopher Short, Matthew S. Mietchen, Eric T. Lofgren
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Oscillation In Mathematical Epidemiology, Meredith Greer
Oscillation In Mathematical Epidemiology, Meredith Greer
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Chronic Kidney Disease From Non-Traditional Causes Throughout Central America, Abigail K. Watson
Chronic Kidney Disease From Non-Traditional Causes Throughout Central America, Abigail K. Watson
Senior Theses
Throughout many Central American countries, incidence of chronic kidney disease (CKD) has been on the rise. The disease mainly affects agricultural workers and differs from typical CKD. Patients in these countries often do not have preexisting conditions such as diabetes or hypertension known to be traditional causes of CKD. They also experience increased damage to the kidney tubules, rather than the glomeruli generally more heavily impacted. There has been speculation regarding the causes of CKDnT (chronic kidney disease of nontraditional causes), but no consensus has been reached. Two major hypotheses to explain the high prevalence among Central American sugarcane workers …
An Analysis Of The Rajasthan Public Health System’S Response To The 2019 Dengue Insurgence, Luke Bryan
An Analysis Of The Rajasthan Public Health System’S Response To The 2019 Dengue Insurgence, Luke Bryan
Independent Study Project (ISP) Collection
Dengue virus is in a pandemic status and is a major public health issue in the modern world. The mosquito-borne disease is largely prevalent in Asia and specifically India, where more than half of the states are considered to have complete presence of the dengue virus. The intricate infrastructure of the Indian public health system looks for dengue cases at all levels and reports to the integrated disease surveillance programme (IDSP).
Analyses of the IDSP and trends of dengue cases was done in response to dengue outbreaks throughout the state. Geographic information system (GIS) maps were created to evaluate a …
Effects Of Dabigatran In Mouse Models Of Aging And Cerebral Amyloid Angiopathy, Neethu Michael, Mher Mahoney Grigoryan, Kelley Kilday, Rachita K. Sumbria, Vitaly Vasilevko, Joanne Van Ryn, David H. Cribbs, Annlia Paganini-Hill, Mark J. Fisher
Effects Of Dabigatran In Mouse Models Of Aging And Cerebral Amyloid Angiopathy, Neethu Michael, Mher Mahoney Grigoryan, Kelley Kilday, Rachita K. Sumbria, Vitaly Vasilevko, Joanne Van Ryn, David H. Cribbs, Annlia Paganini-Hill, Mark J. Fisher
Pharmacy Faculty Articles and Research
Oral anticoagulants are a critical component of stroke prevention, but carry a risk of brain hemorrhage. These hemorrhagic complications tend to occur in elderly individuals, especially those with predisposing conditions such as cerebral amyloid angiopathy (CAA). Clinical evidence suggests that non-vitamin K antagonist oral anticoagulants are safer than traditional oral anticoagulants. We analyzed whether the anticoagulant dabigatran produces cerebral microhemorrhage (the pathological substrate of MRI-demonstrable cerebral microbleeds) or intracerebral hemorrhage in aged mice with and without hemorrhage-predisposing angiopathy. We studied aged (22 months old) Tg2576 (a model of CAA) and wild-type (WT) littermate mice. Mice received either dabigatran etexilate (DE) …
Determining The Relative Transmission Fitness Of Hiv-1 Subtypes A, B, C, And D, Spencer Yeung
Determining The Relative Transmission Fitness Of Hiv-1 Subtypes A, B, C, And D, Spencer Yeung
Electronic Thesis and Dissertation Repository
There is in vivo evidence that suggests the genetic diversity of HIV-1 subtypes influence heterosexual transmission efficiency. To recapitulate sexual transmission in vitro, blocks of genital tissue were exposed to mixtures of genetically different subtype viruses. Migrating immune cells were collected and co-cultured with a CD4+ T-cell line permissive to HIV infection (PM1) to measure dendritic cell virus transfer; HIV-exposed tissues were cultured separately. Next generation sequencing (NGS) of HIV-1 DNA was used to quantify relative infection rates of the various challenge viruses, and to assess fitness differences in infection of the tissue vs. migratory/T cell co-cultures. Our results …
Environmentally Responsible Land Use, Spring/Summer 2010, Issue 22
Environmentally Responsible Land Use, Spring/Summer 2010, Issue 22
Sustain Magazine
No abstract provided.
Sustainable Communities, Fall/Winter 2010, Issue 21
Sustainable Communities, Fall/Winter 2010, Issue 21
Sustain Magazine
No abstract provided.
Sustainable Building, Spring/Summer 2009, Issue 20
Sustainable Building, Spring/Summer 2009, Issue 20
Sustain Magazine
No abstract provided.
Environmental History, Fall/Winter 2009, Issue 19
Environmental History, Fall/Winter 2009, Issue 19
Sustain Magazine
No abstract provided.
Student Research, Spring/Summer 2008, Issue 18
Evolving Pollution Prevention, Fall/Winter 2008, Issue 17
Evolving Pollution Prevention, Fall/Winter 2008, Issue 17
Sustain Magazine
No abstract provided.
Climate Change, Spring/Summer 2007, Issue 16
Our Energy Future, Fall/Winter 2007, Issue 15
Land Conservation, Spring/Summer 2006, Issue 14
Land Conservation, Spring/Summer 2006, Issue 14
Sustain Magazine
No abstract provided.
Pollution And Heart Disease, Fall/Winter 2006, Issue 13
Pollution And Heart Disease, Fall/Winter 2006, Issue 13
Sustain Magazine
No abstract provided.
Green Cities, Spring/Summer 2005, Issue 12
Global Sustainability, Fall/Winter 2005, Issue 11
Global Sustainability, Fall/Winter 2005, Issue 11
Sustain Magazine
No abstract provided.
Environmental Justice, Spring/Summer 2004, Issue 10
Environmental Justice, Spring/Summer 2004, Issue 10
Sustain Magazine
No abstract provided.
Kentucky's Environmental Future, Fall/Winter 2004, Issue 9
Kentucky's Environmental Future, Fall/Winter 2004, Issue 9
Sustain Magazine
No abstract provided.
Urban Ecology, Spring/Summer 2003, Issue 8
Urban Regeneration, Fall/Winter 2003, Issue 7
Urban Air Quality, Spring/Summer 2002, Issue 6
Sustainability Of Industrialized Agriculture, Fall/Winter 2002, Issue 5
Sustainability Of Industrialized Agriculture, Fall/Winter 2002, Issue 5
Sustain Magazine
No abstract provided.
Urban Design For Environmental Protection, Spring/Summer 2001, Issue 4
Urban Design For Environmental Protection, Spring/Summer 2001, Issue 4
Sustain Magazine
No abstract provided.