Operations Research, Systems Engineering and Industrial Engineering Commons^™

Reliability Modeling And Improvement Of Critical Infrastructures: Theory, Simulation, And Computational Methods, José Carlos Hernández Azucena

Graduate Theses and Dissertations

This dissertation presents a framework for developing data-driven tools to model and improve the performance of Interconnected Critical Infrastructures (ICIs) in multiple contexts. The importance of ICIs for daily human activities and the large volumes of data in continuous generation in modern industries grant relevance to research efforts in this direction. Chapter 2 focuses on the impact of disruptions in Multimodal Transportation Networks, which I explored from an application perspective. The outlined research directions propose exploring the combination of simulation for decision-making with data-driven optimization paradigms to create tools that may provide stakeholders with optimal policies for a wide array …

Enabling The “Easy Button” For Broad, Parallel Optimization Of Functions Evaluated By Simulation, Andrew Gibson

Graduate Theses and Dissertations

Java Optimization by Simulation (JOBS) is presented: an open-source, object-oriented Java library designed to enable the study, research, and use of optimization for models evaluated by simulation. JOBS includes several novel design features that make it easy for a simulation modeler, without extensive expertise in optimization or parallel computation, to define an optimization model with deterministic and/or stochastic constraints, choose one or more metaheuristics to solve it and run, using massively parallel function evaluation to reduce wall-clock times.

JOBS is supported by a new language independent, application programming interface (API) for remote simulation model evaluation and a serverless computing environment …

Modeling Of Complex Parts For Industrial Waterjet Cleaning, Braden James

Graduate Theses and Dissertations

Industrial high-pressure waterjet cleaning is common to many industries. The modeling in this paper functions inside a collaborative robotic framework for high mix, low volume processes where human robot collaboration is beneficial. Automation of pressure washing is desirable for economic and ergonomic reasons. An automated cleaning system needs path simulation and analysis to give the operator insight into the predicted cleaning performance of the system. In this paper, ablation, the removal of a substrate coating by waterjet, is modeled for robotic cleaning operations. The model is designed to work with complex parts often found in spray cleaning operations, namely parts …

Personalized Decision Modeling For Intervention And Prevention Of Cancers, Fan Wang

Graduate Theses and Dissertations

Personalized medicine has been utilized in all stages of cancer care in recent years, including the prevention, diagnosis, treatment and follow-up. Since prevention and early intervention are particularly crucial in reducing cancer mortalities, personalizing the corresponding strategies and decisions so as to provide the most appropriate or optimal medical services for different patients can greatly improve the current cancer control practices. This dissertation research performs an in-depth exploration of personalized decision modeling of cancer intervention and prevention problems. We investigate the patient-specific screening and vaccination strategies for breast cancer and the cancers related to human papillomavirus (HPV), representatively. Three popular …