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Full-Text Articles in Operations Research, Systems Engineering and Industrial Engineering
History Of Food Acceptance Research In The Us Army, Herbert L. Meiselman, Howard G. Schutz
History Of Food Acceptance Research In The Us Army, Herbert L. Meiselman, Howard G. Schutz
US Army Research
The history of food acceptance research by the US Army in Chicago and Natick is reviewed. The review covers the staff of the two research centers, the research programs, and the significant accomplishments of the Army laboratories from the 1940s to the present. Accomplishments begin with the development of the nine-point hedonic scale, and the development of the first Food Acceptance Laboratory. Further accomplishments include studies of sensory psychophysics, food preferences, food choice and food intake. The laboratories designed methods and conducted research on the role of consumer variables in the acceptance of food products and food service systems. Recent …
Rodent Sperm Analysis In Field-Based Ecological Risk Assessment: Pilot Study At Ravenna Army Ammunition Plant, Ravenna, Ohio, Lawrence V. Tannenbaum, Matthew Bazar, Melanie S. Hawkins, Barney W. Cornaby, Elizabeth A. Ferguson, L. Chantelle Carroll, Patrick F. Ryan
Rodent Sperm Analysis In Field-Based Ecological Risk Assessment: Pilot Study At Ravenna Army Ammunition Plant, Ravenna, Ohio, Lawrence V. Tannenbaum, Matthew Bazar, Melanie S. Hawkins, Barney W. Cornaby, Elizabeth A. Ferguson, L. Chantelle Carroll, Patrick F. Ryan
US Army Research
Ecological risk assessment (ERA) guidance recommends that field-truthing efforts proceed when modeled hazard quotients (HQs) suggest that toxicological effects are occurring to site receptors. To date, no field methods have been proposed by the regulatory community that can lead to definitive determinations of acceptable or unacceptable risk for birds and mammals, the two terrestrial classes of receptors that are commonly assessed using the HQ method. This paper describes rodent sperm analysis (RSA) as a viable method to be applied in the field at sites with historical contamination. RSA is capable of detecting biological differences that bear on reproduction, a highly …
The Prevalence And Severity Of Coronary Artery Calcification On Coronary Artery Computed Tomography In Black And White Subjects, Timothy C. Lee, Patrick G. O’Malley, Irwin Feuerstein, Allen J. Taylor
The Prevalence And Severity Of Coronary Artery Calcification On Coronary Artery Computed Tomography In Black And White Subjects, Timothy C. Lee, Patrick G. O’Malley, Irwin Feuerstein, Allen J. Taylor
US Army Research
OBJECTIVES We studied the relationship between coronary artery calcium (CAC) and race in asymptomatic, active-duty personnel in the Prospective Army Coronary Calcium (PACC) project.
BACKGROUND Valid cardiovascular risk assessments in black Americans using coronary artery computed tomography (coronary CT) require the generalizability of population-based CAC score distributions derived from primarily white patient populations.
METHODS Among 1,000 consecutive participants (mean age, 42 ± 2 years; range, 40 to 45 years), 999 participants underwent coronary CT and indicated a specific racial affiliation. This included white, non-Hispanic in 699 (69.9%) participants and black, non-Hispanic in 194 (19.4%) participants. Univariate associations between race and …
Novel Small Molecule Inhibitors Of Botulinum Neurotoxin A Metalloprotease Activity, James C. Burnett, James J. Schmidt, Robert G. Stafford, Rekha G. Panchal, Tam L. Nguyen, Ann R. Hermone, Jonathan L. Vennerstrom, Connor F. Mcgrath, Douglas J. Lane, Edward A. Sausville, Daniel W. Zaharevitz, Rick Gussio, Sina Bavari
Novel Small Molecule Inhibitors Of Botulinum Neurotoxin A Metalloprotease Activity, James C. Burnett, James J. Schmidt, Robert G. Stafford, Rekha G. Panchal, Tam L. Nguyen, Ann R. Hermone, Jonathan L. Vennerstrom, Connor F. Mcgrath, Douglas J. Lane, Edward A. Sausville, Daniel W. Zaharevitz, Rick Gussio, Sina Bavari
US Army Research
Botulinum neurotoxins (BoNTs) are among the most lethal biological substances to have been weaponized and are listed as biodefense category A agents. Currently, no small molecule (non-peptidic) therapeutics exist to counter this threat; hence, identifying and developing compounds that inhibit BoNTs is a high priority. In the present study, a high-throughput assay was used to identify small molecules that inhibit the metalloprotease activity of BoNT serotype A light chain (BoNT/A LC). All inhibitors were further verified using a HPLC-based assay. Conformational analyses of these compounds, in conjunction with molecular docking studies, were used to predict structural features that contribute to …
Diet And Physical Performance, Scott J. Montain, Andrew J. Young
Diet And Physical Performance, Scott J. Montain, Andrew J. Young
US Army Research
This paper provides a historical summary of military nutrition research into the role of diet for sustaining soldier physical performance. Studies of underfeeding document that physical performance is preserved during several days of underfeeding provided sufficient carbohydrate and minerals are consumed to minimize the diuresis associated with semi-starvation diets and serial intake of carbohydrate is available to support metabolism during prolonged work. The Military Recommended Dietary Allowances, AR 40-25, currently recommends that when restricted rations are required, that the ration contain at least 1100–1500 kcal, 50–70 g of protein, and a minimum of 100 g of carbohydrate on a daily …
Retrieval Of Subpixel Snow-Covered Area And Grain Size From Imaging Spectrometer Data, Thomas H. Painter, Jeff Dozier, Dar A. Roberts, Robert E. Davis, Robert O. Green
Retrieval Of Subpixel Snow-Covered Area And Grain Size From Imaging Spectrometer Data, Thomas H. Painter, Jeff Dozier, Dar A. Roberts, Robert E. Davis, Robert O. Green
US Army Research
We describe and validate an automated model that retrieves subpixel snow-covered area and effective grain size from Airborne Visible/ Infrared Imaging Spectrometer (AVIRIS) data. The model analyzes multiple endmember spectral mixtures with a spectral library of snow, vegetation, rock, and soil. We derive snow spectral endmembers of varying grain size from a radiative transfer model; spectra for vegetation, rock, and soil were collected in the field and laboratory. For three AVIRIS images of Mammoth Mountain, California that span common snow conditions for winter through spring, we validate the estimates of snow-covered area with fine-resolution aerial photographs and validate the estimates …
A Biologic Model For Assessment Of Osseous Strain Patterns And Plating Systems In The Human Maxilla, L. Russell Alberts, Kenneth O. Phillips, Harold K. Tu, Warren W. Stinson, Andrew Friedman
A Biologic Model For Assessment Of Osseous Strain Patterns And Plating Systems In The Human Maxilla, L. Russell Alberts, Kenneth O. Phillips, Harold K. Tu, Warren W. Stinson, Andrew Friedman
US Army Research
Purpose: This study was conducted to examine a biomechanical model and to help answer fundamental questions that relate to rigid plate fixation in the maxilla. Specifically, we sought to elucidate the principal strain patterns generated in the maxilla secondary to masticatory forces as well as the amount of permanent deformational changes incurred due to these loading forces.
Materials and Methods: Cadaveric heads with the mandible removed were defleshed and placed in a 2-part testing rig to hold and position the skull for testing in a standard material testing system. Rosette strain gages were attached at predefined points on the skull, …
Military Leadership: A Context Specific Review, Leonard Wong, Paul Bliese, Dennis Mcgurk
Military Leadership: A Context Specific Review, Leonard Wong, Paul Bliese, Dennis Mcgurk
US Army Research
The purpose of this article is to review the literature on military leadership and highlight research opportunities for leadership scholars. The review uses a context specific approach and turns to a simplified version of Hunt’s (Hunt, J. G. (1991). Leadership: A new synthesis. Newbury Park, CA: Sage) extended multilevel leadership model as a template to examine the many facets of military leadership. The military leadership literature is stratified into the systems, organizational, and direct levels of leadership with an examination of studies on the critical tasks and individual capabilities required at each level. Additionally, studies on organizational culture and effectiveness …
Protracted Protection To Plasmodium Berghei Malaria Is Linked To Functionally And Phenotypically Heterogeneous Liver Memory Cd8+ T Cells1, Dmitri Berenzon, Robert J. Schwenk, Lisa Letellier, Mimi Guebre-Xabier, Jackie Williams, Urszula Krzych
Protracted Protection To Plasmodium Berghei Malaria Is Linked To Functionally And Phenotypically Heterogeneous Liver Memory Cd8+ T Cells1, Dmitri Berenzon, Robert J. Schwenk, Lisa Letellier, Mimi Guebre-Xabier, Jackie Williams, Urszula Krzych
US Army Research
We previously demonstrated that protection induced by radiation-attenuated (y) Plasmodium berghei sporozoites is linked to MHC class I-restricted CD8+ T cells specific for exoerythrocytic-stage Ags, and that activated intrahepatic memory CD8+ T cells are associated with protracted protection. In this study, we further investigated intrahepatic memory CD8+ T cells to elucidate mechanisms required for their maintenance. Using phenotypic markers indicative of activation (CD44, CD45RB), migration (CD62L), and IFN-y production, we identified two subsets of intrahepatic memory CD8+ T cells: the CD44highCD45RBlowCD62LlowCD122low phenotype, representing the dominant effector …