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Operations Research, Systems Engineering and Industrial Engineering Commons

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Full-Text Articles in Operations Research, Systems Engineering and Industrial Engineering

Feature-Based Discretization Of A Turbine Disk For Probabilistic Risk Assessment, Michael Thomas, Jace Carter, Lloyd Matson, Tarun Goswami Aug 2018

Feature-Based Discretization Of A Turbine Disk For Probabilistic Risk Assessment, Michael Thomas, Jace Carter, Lloyd Matson, Tarun Goswami

Biomedical, Industrial & Human Factors Engineering Faculty Publications

There is an economic need to extend the useful life of jet engine rotors. Retirement-for-Cause (RFC) is a lifing method that allows for the continued operation of components passed traditional life limits. Under RFC, an extension of damage tolerance, components are deemed safe for a further service interval using non-destructive inspections (NDI) for crack like defe cts. As components are kept in-service beyond their designed service life it is essential that the probability of failure (POF), or risk, of continued service is known. Under current FAA rotor design certification practices the component POF is analyzed using a probabilistic framework focused …


Failure Analysis Of Philos Plate Construct Used For Pantalar Arthrodesis Paper Ii-Screws And Fem Simulations, Farah Hamandi, Richard T. Laughlin, Tarun Goswami Apr 2018

Failure Analysis Of Philos Plate Construct Used For Pantalar Arthrodesis Paper Ii-Screws And Fem Simulations, Farah Hamandi, Richard T. Laughlin, Tarun Goswami

Biomedical, Industrial & Human Factors Engineering Faculty Publications

A fractured stainless steel 3.5 mm proximal humerus internal locking system (PHILOS) plate and screws were investigated in this paper. This plate was used for ankle arthrodesis of a 68-year-old female with a right ankle deformity. Both the plate and screws were considered in this investigation. Optical and scanning electron microscopes (SEM) were used to document fracture surface characteristics, such as extensive scratching, plastic deformation, rubbed surfaces, discoloration, and pitting, along with cleavage, secondary cracking, deposits of debris, striations, and dimples. Indications of these features show that the plate failed by corrosion fatigue, however, overloading separated the screw(s) in two …


Developing A High-Dimensional Dataset Of The Changes In Ion Channels Expression Level At The Cholinergic Boutons In Amyotrophic Lateral Sclerosis, Joshua Harris Jan 2018

Developing A High-Dimensional Dataset Of The Changes In Ion Channels Expression Level At The Cholinergic Boutons In Amyotrophic Lateral Sclerosis, Joshua Harris

The University Honors Program

ALS, or Amyotrophic Lateral Sclerosis, is a neurodegenerative disease that causes motor neuron degeneration. Affecting nerve cells in the brain and spinal cord, this disease eventually leads to respiratory muscle failure and death. Although ALS is fairly uncommon, our lack of information on how ALS develops drives the need for further study. In the Neuro Engineering, Rehabilitation, and Degeneration laboratory at Wright State University, immunohistochemical data has been collected on a mouse model (SOD1-G93A) throughout their lifespan to better examine the neurological effects of ALS. To better organize and interpret the data, a high-dimensional dataset was created in this project …