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Articles 61 - 64 of 64
Full-Text Articles in Nanoscience and Nanotechnology
Bio-Nano Interfaces: Enzyme Immobilization For Biomimetic Energy Harvesting, Rachel Hjelm
Bio-Nano Interfaces: Enzyme Immobilization For Biomimetic Energy Harvesting, Rachel Hjelm
Nanoscience and Microsystems ETDs
In the face of todays rapidly growing energy demands accompanied by limited, non-renewable supplies, development of novel energy alternatives that are both renewable and inexpensive has become more important than ever. Development of 3D structures exploring the properties of nano-materials and biological molecules has been shown through the years as an effective path forward for the design of advanced bio-nano architectures for enzymatic fuel cells (EFCs). Despite advantages over conventional fuel cells, EFCs still suffer from several problems including low efficiency and stability. Overcoming these limitations in order to make them more viable for real world application is an ongoing …
Visualizing Mast Cell Activation: Single Molecule Dynamics Of Early Events In Fceri Signaling, Samantha Schwartz
Visualizing Mast Cell Activation: Single Molecule Dynamics Of Early Events In Fceri Signaling, Samantha Schwartz
Nanoscience and Microsystems ETDs
Healthy immune cell behavior requires sensitive and robust control over the processes that regulate signal transduction. In this work we employ single molecule fluorescence imaging techniques to quantify adapter protein recruitment, lateral mobility, receptor aggregation, and cytoskeletal organization to create a better understanding of many key processes in immune cell regulation. We focus on understanding the initiating events in FceRI signaling in mast cells. Mast cell signaling encompassing a wide array of cellular outcomes including calcium flux, release of pre-formed inflammatory mediators and the production of cytokines. Careful control over appropriate reactions to external antigens is necessary for mast cells …
Electrodeposition Of High Magnetostrictive Cobalt Iron Alloy Films For Smart Tags And Sensor Applications, Jamin Pillars
Electrodeposition Of High Magnetostrictive Cobalt Iron Alloy Films For Smart Tags And Sensor Applications, Jamin Pillars
Nanoscience and Microsystems ETDs
Magnetostrictive CoFe films were investigated for use as magnetoelastic tags or sensors. The ability to electrodeposit these films enables batch fabrication processes to pattern a variety of geometries while controlling the film stoichiometry and crystallography. In current research looking at CoFe, improved magnetostriction was achieved using a co-sputtering, annealing, and quenching method1. Other current research has reported electrodeposited CoFe films using a sulfate based chemistry resulting in film compositions that are Fe rich in the range of Co0.3-0.4Fe0.7-0.6 and have problems of co-deposition of undesirables that can have a negative impact on magnetic properties2, 3. The research presented here focused …
Efficacy Of A Magnetic Drug Delivery System And Development Of An Orthotopic Lung Tumor Imaging Model, Amber Mcbride
Efficacy Of A Magnetic Drug Delivery System And Development Of An Orthotopic Lung Tumor Imaging Model, Amber Mcbride
Nanoscience and Microsystems ETDs
The aim of this work was the development of a novel drug delivery vehicle termed nano-in-microparticles (NIMs) to evaluate the magnetic-field dependent targeting of dry powder NIMs administered endotracheally using an ex vivo and in vivo rodent model. NIMs are a novel dry powder drug delivery vehicle containing 70% lactose (w/w), 20% SPIONs (w/w) and 10% fluorescent nanospheres (w/w). Mice were insufflated with NIMs delivery vehicle in the presence of magnetic field dependent targeting to the left ventral lung after thoracotomy; controls were insufflated with the NIMs in the absence of magnetic field dependent targeting. Quantification of deposition of the …