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Applied Mechanics Commons

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Full-Text Articles in Applied Mechanics

Modeling Of Swimming Cells From Nano-Scale To Micro-Scale, Yicheng Zhao May 2018

Modeling Of Swimming Cells From Nano-Scale To Micro-Scale, Yicheng Zhao

McKelvey School of Engineering Theses & Dissertations

Certain human genetic diseases -- primary ciliary dyskinesia, infertility, and hydrocephalus -- are characterized by changes in beat frequency and waveform of cilia and flagella. Chlamydomonas reinhardtii, which is a single-cell green alga about ten micrometers in diameter that swims with two flagella, serves as an excellent biological model because its flagella share the same structure and genetic background as mammalian cilia and flagella. This study uses the finite element method to investigate the behavior of C. reinhardtii swimming from nano-scale to micro-scale. At the device-level, micro-scale modeling indicates that well-designed acoustic microfluidic devices can be used to trap groups …


Numerical Simulation Of A High Strain Rate Biaxial Compression Apparatus, Michael Lagieski Apr 2018

Numerical Simulation Of A High Strain Rate Biaxial Compression Apparatus, Michael Lagieski

McKelvey School of Engineering Theses & Dissertations

Few experimental methods today are capable of exploring the strength of materials at high strain rates (105 s-1). Those that are capable, such as the Split Hopkinson Bar, Taylor Anvil and Plate Impact suffer from instability and are generally limited to one dimensional wave propagation. Of particular interest is material response under biaxial compression, similar to that seen in inertial confinement fusion. Laser fusion fuel pellets typically undergo large strain rates as well as plastic deformation and non-linear behavior. This work briefly outlines an experimental procedure designed to replicate these large strain rates under biaxial compression using …