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Full-Text Articles in Mechanical Engineering
Considering The Influence Of Coronary Motion On Artery‑Specific Biomechanics Using Fluid–Structure Interaction Simulation, Nicholas A. T. Fogell, Miten Patel, Pan Yang, Roosje M. Ruis, David B. Garcia, Jarka Naser, Fotios Savvopoulos, Clint Davies Taylor, Anouk L. Post, Ryan M. Pedrigi, Ranil De Silva, Rob Krams
Considering The Influence Of Coronary Motion On Artery‑Specific Biomechanics Using Fluid–Structure Interaction Simulation, Nicholas A. T. Fogell, Miten Patel, Pan Yang, Roosje M. Ruis, David B. Garcia, Jarka Naser, Fotios Savvopoulos, Clint Davies Taylor, Anouk L. Post, Ryan M. Pedrigi, Ranil De Silva, Rob Krams
Department of Mechanical and Materials Engineering: Faculty Publications
The endothelium in the coronary arteries is subject to wall shear stress and vessel wall strain, which influences the biology of the arterial wall. This study presents vessel-specific fluid–structure interaction (FSI) models of three coronary arteries, using directly measured experimental geometries and boundary conditions. FSI models are used to provide a more physiologically complete representation of vessel biomechanics, and have been extended to include coronary bending to investigate its effect on shear and strain. FSI both without- and with-bending resulted in significant changes in all computed shear stress metrics compared to CFD (p = 0.0001). Inclusion of bending within …
Optimization Of Microfluidic Particle Separator Geometry Using Computational Fluid Dynamics, Joseph Petersen
Optimization Of Microfluidic Particle Separator Geometry Using Computational Fluid Dynamics, Joseph Petersen
Electronic Theses and Dissertations
Computational fluid dynamics software was used to simulate the motion of circulating tumor cells in a variety of microfluidic cell isolation devices. Design of several novel microfluidic cell isolation devices was aided by viewing streamlines of fluid in devices in simulation. Devices that performed best in simulation used 5-micrometer wide guiding channels to guide cells to the capture location in the device. While these devices performed better than other devices in simulation and captured all particles regardless of position along inlet, experimental results differ from simulation.
Cfd Analysis Of 3-D Thermalhydraulics Flow Effects On Wall Concentration Gradient Profiles For Lbe Loop Fittings, Narain Armbya
Cfd Analysis Of 3-D Thermalhydraulics Flow Effects On Wall Concentration Gradient Profiles For Lbe Loop Fittings, Narain Armbya
UNLV Theses, Dissertations, Professional Papers, and Capstones
The objective of the thesis is to study the effects of thermalhydraulics flows on the wall concentration gradient profiles in LBE loop fittings. To that end detailed models of the fittings have been constructed to study these effects. These fittings include sudden expansion, sudden contraction, t-joint and elbow. The typical flow rates chosen for these simulations are typical of design criteria chosen for the loop with Reynolds numbers expected around 200,000 and the usual axial temperature profiles which are being characterized in the DELTA loop at LANL. STAR-CD is the simulation package used to make these predictions, which include detailed …
Chemical Kinetics And Thermal Hydraulics Of Lead Bismuth Flow Loops, Kanthi Kiran Dasika
Chemical Kinetics And Thermal Hydraulics Of Lead Bismuth Flow Loops, Kanthi Kiran Dasika
UNLV Theses, Dissertations, Professional Papers, and Capstones
The objective of the thesis is to study the effect of chemical kinetics and thermal hydraulics of Lead Bismuth Eutectic (LBE) flow in the Materials Test Loop (MTL). The Materials Test Loop, also known as the Delta Loop, was built in Los Alamos National Laboratories (LANL) to obtain the experimental data for corrosion estimation and analysis. It is a well-known fact that corrosion plays an important role in the design of nuclear thermal hydraulic systems. Since the MTL is a multi-section closed system that differs in diameter from one part to another, an intensive study on the overall and regional …