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Full-Text Articles in Mechanical Engineering
The Effect Of Bone And Ligament Morphology Of Ankle Joint Loading In The Neutral Position, Jinhyuk Kim
The Effect Of Bone And Ligament Morphology Of Ankle Joint Loading In The Neutral Position, Jinhyuk Kim
Mechanical & Aerospace Engineering Theses & Dissertations
Computational modeling of joints is used to investigate the effect of injuries, to plan surgeries, and to answer questions about joints that cannot be answered experimentally. Existing models of the ankle joint are moving toward being able to model specific patients, however, they do not include all of the anatomy (e.g., bones and/or ligaments) and have restrictive boundary conditions. These simplification in anatomy are made to minimize pre-processing and computation time. Because biomechanical modeling is increasingly focused on the implementation of patient specific cases, the effects of including more anatomical structures and determining how they affect the model results is …
Biophysical Tools To Study Cellular Mechanotransduction, Ismeel Muhamed, Farhan Chowdhury, Venkat Maruthamuthu
Biophysical Tools To Study Cellular Mechanotransduction, Ismeel Muhamed, Farhan Chowdhury, Venkat Maruthamuthu
Mechanical & Aerospace Engineering Faculty Publications
The cell membrane is the interface that volumetrically isolates cellular components from the cell's environment. Proteins embedded within and on the membrane have varied biological functions: reception of external biochemical signals, as membrane channels, amplification and regulation of chemical signals through secondary messenger molecules, controlled exocytosis, endocytosis, phagocytosis, organized recruitment and sequestration of cytosolic complex proteins, cell division processes, organization of the cytoskeleton and more. The membrane's bioelectrical role is enabled by the physiologically controlled release and accumulation of electrochemical potential modulating molecules across the membrane through specialized ion channels (e.g., Na⁺, Ca2+, K⁺ channels). …