Mechanical Engineering Commons^™

A Parametric Investigation Of A Novel, Modular, Gasketless, Microfluidic Interconnect Using Parallel Superhydrophobic Surfaces, Christopher Ramsey Brown

LSU Master's Theses

The gasketless microfluidic interconnect has the potential to offer a standardized approach to interconnects between modular microfluidic components. This strategy uses parallel superhydrophobic surfaces (contact angle ≥ 150ᴼ) to passively seal adjacent, concentric, microfluidic ports separated by an air gap using a liquid bridge created between the chips. The parallel superhydrophobic surfaces do not require the addition of a gasket or other additional components so that the assembly process scales favorably with an increasing number of fluidic interconnects. The gasketless seal does not contribute to geometric constraint between the component chips which allows alignment between chips to scale favorably with …

Pdms Based Waveguides For Microfluidics And Eocb, Weiping Qiu

LSU Master's Theses

Due to the low cost, fast and ease of molding, PDMS has become one of the most popular materials for microfluidics devices, bioMEMS applications. Meanwhile, the integration of different functional components on to one single chip (or Lab on a Chip) is the dream for many scientists and engineers in the related area. In addition to the necessary mechanical components for accommodating the reactions, such as pumps, valves, mixers and so on, optical components such as waveguides, lens, interferers are all desired to be lumped into such a system.

The waveguide for such a system requires the material to have …

Simulations And Experimental Analysis Of High-Aspect-Ratio Diffusive Micro-Mixers, Amit Maha

LSU Master's Theses

Passive (diffusional) mixing has been used in designing high-aspect-ratio micro-mixers for the purpose of performing the Liagase Detection Reaction (LDR). A simple model was used to design such mixers optimized for pressure drop or time required to deliver a prescribed volume of mixture. The types of mixers considered are simple, cheap, and durable and can perform over a broad range of volumetric flow rates at reasonably modest pressure drops. The fluids typically have a very low diffusion coefficient of=1.2x10^10m^2/s, and thus diffusional mixing can only be effective in high-aspect-ratio micro-channels. A realizable aspect ratio of 6 has been considered initially …