Mechanical Engineering Commons^™

Study On The Chemical And Mechanical Stability Of Polymer Nanofluidic Biosensors, Dae Won Kim

LSU Master's Theses

Polymer nanofluidic devices have great potential to replace silicon (Si) and glass-based nanofluidic devices in biomedical applications due to their advantages such as low material and fabrication cost, various physicochemical properties, well-developed surface modification protocol, and low electrical noises for electrical measurements. In nanofluidic sensing applications, single molecules such as DNA are introduced into the fabricated nanochannel or nanopore, measuring their physicochemical properties optically or electrically. The properties of materials for nanofluidic devices have a significant role in the performance of the devices, such as DNA translocation and device stability.

Among several nanoscale fluidic physics, surface charge density is a …