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Biomedical Engineering and Bioengineering

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2011

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Articles 31 - 38 of 38

Full-Text Articles in Mechanical Engineering

Role Of Hydrodynamic Behavior Of Dna Molecules In Dielectrophoretic Polarization Under The Action Of An Electric Field, Hui Zhao Jan 2011

Role Of Hydrodynamic Behavior Of Dna Molecules In Dielectrophoretic Polarization Under The Action Of An Electric Field, Hui Zhao

Mechanical Engineering Faculty Research

A continuum model is developed to predict the dielectrophoretic polarizability of coiled DNA molecules under the action of an alternating current electric field. The model approximates the coiled DNA molecule as a charged porous spherical particle. The model explains the discrepancies among scaling laws of polarizability of different-sized DNA molecules with contour length and such discrepancies are attributed to different hydrodynamic behavior. With zero or one fitting parameter, theoretical predictions are in good agreement with various experimental data, even though in experiments there are some uncertainties in regard to certain parameters.


Using Thermally Coupled Reactive Distillation Columns In Biodiesel Production, Nghi Nguyen, Yaşar Demirel Jan 2011

Using Thermally Coupled Reactive Distillation Columns In Biodiesel Production, Nghi Nguyen, Yaşar Demirel

Yaşar Demirel Publications

Production of ethyl dodecanoate (biodiesel) using lauric acid and methanol with a solid acid catalyst of sulfated zirconia is studied by using two distillation sequences. In the first sequence, the methanol recovery column follows the reactive distillation column. In the second sequence, the reactive distillation and methanol recovery columns are thermally coupled. Thermally coupled distillation sequences may consume less energy by allowing interconnecting vapor and liquid streams between the two columns to elminate reboiler or condenser or both. Here we study the thermally coupled side-stripper reactive distillation and eliminate the condenser of the reactive distillation column. Both the sequences are …


Creep Behaviour Of Hand Laminated Glass Reinforced Polymer Composites., Brain Quinn Jan 2011

Creep Behaviour Of Hand Laminated Glass Reinforced Polymer Composites., Brain Quinn

Theses

The creep behaviour of hand laminated, glass fiber reinforced polyester composites were studied at coupon level, due to the use of similar materials in long term load bearing civil and structural engineering applications. Creep predictions were made by fitting the parameters of several viscoelastic models to experimental creep data as well as two accelerated test methods, time temperature superposition (TTS) and frequency time transformations (FTT). TTS experiments were carried out in a dynamic mechanical analyzer (DMA) in three point bending mode for three types of material systems. Creep compliance master curves representing the linear viscoelastic creep response at reference temperatures …


Nitric Oxide-Generating Silicone As A Blood-Contacting Biomaterial, Kagya Amoako Jan 2011

Nitric Oxide-Generating Silicone As A Blood-Contacting Biomaterial, Kagya Amoako

Mechanical and Industrial Engineering Faculty Publications

Coagulation upon blood-contacting biomaterials remains a problem for short and long-term clinical applications. This study examined the ability of copper(II)-doped silicone surfaces to generate nitric oxide (NO) and locally inhibit coagulation. Silicone was doped with 3-micron copper (Cu(0)) particles yielding 3 to 10 weight percent (wt%) Cu in 70-μm thick Cu/Silicone polymeric matrix composites (Cu/Si PMCs). At 3, 5, 8 and 10 wt% Cu doping, the surface expression of Cu was 12.1 ± 2.8%, 19.7 ± 5.4%, 29.0 ± 3.8%, and 33.8 ± 6.5% respectively. After oxidizing Cu(0) to Cu(II) by spontaneous corrosion, NO flux, JNO (mol*cm−2*min−1), as measured by …


Finite Element Reconstruction Of Real World Aortic Injury In Near-Side Lateral Automotive Crashes With Conceptual Countermeasures, Aditya Neelakanta Belwadi Jan 2011

Finite Element Reconstruction Of Real World Aortic Injury In Near-Side Lateral Automotive Crashes With Conceptual Countermeasures, Aditya Neelakanta Belwadi

Wayne State University Dissertations

Traumatic rupture of the aorta (TRA) remains the second most common cause of death associated with motor vehicle crashes after brain injury. On an average, nearly 8,000 people die annually in the United States due to blunt injury to the aorta. It is observed that more than 80% of occupants who suffer an aortic injury die at the scene due to exsanguination into the chest. With the advent of more accurate and established human body finite element (FE) models, FE crash reconstruction methods may become a valuable tool when assessing crash scenarios and occupant injury mechanisms.

The current study is …


Estimation Of The Centre Of Mass From Motion Capture And Force Plate Recordings: A Study On The Elderly, Sebastien Cotton, Michele Vanoncini, Philippe Fraisse, Nacim Ramdani, Emel Demircan, Andrew P. Murray, Thierry Keller Jan 2011

Estimation Of The Centre Of Mass From Motion Capture And Force Plate Recordings: A Study On The Elderly, Sebastien Cotton, Michele Vanoncini, Philippe Fraisse, Nacim Ramdani, Emel Demircan, Andrew P. Murray, Thierry Keller

Mechanical and Aerospace Engineering Faculty Publications

The estimation of the centre of mass position in humans is usually based on biomechanical models developed from anthropometric tables. This method can potentially introduce errors in studies involving elderly people, since the ageing process is typically associated with a modification of the distribution of the body mass. In this paper, an alternative technique is proposed, and evaluated with an experimental study on 9 elderly volunteers. The technique is based on a virtual chain, identified from experimental data and locating the subject's centre of mass. Its configuration defines the location of the centre of mass, and is a function of …


A Microfluidic Device For Impedance Spectroscopy, Ahmet Can Sabuncu Jan 2011

A Microfluidic Device For Impedance Spectroscopy, Ahmet Can Sabuncu

Mechanical & Aerospace Engineering Theses & Dissertations

Recently, microfluidics has become a versatile tool to investigate cellular biology and to build novel biomedical devices. Dielectric spectroscopy, on the other hand, allows non-invasive probing of biological cells. Information on the cell membrane, cytoplasm, and nucleus can be obtained by dielectric spectroscopy provided that appropriate tools are used in specific frequency ranges. This dissertation includes fabrication, characterization, and testing of a simple microfluidic device to measure cell dielectric properties. The dielectric measurements are performed on human T-cell leukemia (Jurkat), mouse melanoma (B16), mouse hepatoma (Hepa), and human costal chondrocyte cells. Dielectric measurements consist of measuring the complex impedance of …


Thermal Modelling For Laser Treatment Of Port Wine Stains, Dong Li, Guo-Xiang Wang, Yaling He Dec 2010

Thermal Modelling For Laser Treatment Of Port Wine Stains, Dong Li, Guo-Xiang Wang, Yaling He

Dr. Guo-Xiang Wang

No abstract provided.