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Other Materials Science and Engineering Commons

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2011

Ciprofloxacin; grafting; Acrylic acid; biodegradability

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Full-Text Articles in Other Materials Science and Engineering

Preparation And Characterisation Of Graft Biopolymer To Improve Sustained Release Property, Ajit Behera Jan 2011

Preparation And Characterisation Of Graft Biopolymer To Improve Sustained Release Property, Ajit Behera

Ajit Behera

In the present piece of research work focuses on grafting Acrylic acid with HPMC to obtain copolymers with improved properties, biodegradable and biocompatible that will be used as hydrogel or water absorbing polymers. To develop a prolong release activity drug delivery system for the medication purpose to enhance drug activity and reduce the frequency of dose via this hydrogel. A novel HPMC-g- acrylic acid hydrogel was prepared by in-situ emulsifier free emulsion polymerization using benzyl peroxide as an initiator through 1-stage grafting. Acrylic Acid could intercalate into layers of HPMC and form graft composites through in situ graftpolymerization with acrylic …