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Full-Text Articles in Signal Processing
One-Dimensional Multi-Frame Blind Deconvolution Using Astronomical Data For Spatially Separable Objects, Marc R. Brown
One-Dimensional Multi-Frame Blind Deconvolution Using Astronomical Data For Spatially Separable Objects, Marc R. Brown
Theses and Dissertations
Blind deconvolution is used to complete missions to detect adversary assets in space and to defend the nation's assets. A new algorithm was developed to perform blind deconvolution for objects that are spatially separable using multiple frames of data. This new one-dimensional approach uses the expectation-maximization algorithm to blindly deconvolve spatially separable objects. This object separation reduces the size of the object matrix from an NxN matrix to two singular vectors of length N. With limited knowledge of the object and point spread function the one-dimensional algorithm successfully deconvolved the objects in both simulated and laboratory data.
Measuring Localization Confidence For Quantifying Accuracy And Heterogeneity In Single-Molecule Super-Resolution Microscopy, Hesam Mazidi, Tianben Ding, Arye Nehorai, Matthew D. Lew
Measuring Localization Confidence For Quantifying Accuracy And Heterogeneity In Single-Molecule Super-Resolution Microscopy, Hesam Mazidi, Tianben Ding, Arye Nehorai, Matthew D. Lew
Electrical & Systems Engineering Publications and Presentations
We present a computational method, termed Wasserstein-induced flux (WIF), to robustly quantify the accuracy of individual localizations within a single-molecule localization microscopy (SMLM) dataset without ground- truth knowledge of the sample. WIF relies on the observation that accurate localizations are stable with respect to an arbitrary computational perturbation. Inspired by optimal transport theory, we measure the stability of individual localizations and develop an efficient optimization algorithm to compute WIF. We demonstrate the advantage of WIF in accurately quantifying imaging artifacts in high-density reconstruction of a tubulin network. WIF represents an advance in quantifying systematic errors with unknown and complex distributions, …