Controls and Control Theory Commons^™

Adaptive Personalized Drug Delivery Method For Warfarin And Anemia Management: Modeling And Control., Affan Affan

Electronic Theses and Dissertations

Personalized precision medicine aims to develop the appropriate treatments for suitable patients at the right time to obtain optimal results. Personalized medicine is challenging due to inter- and intra-patient variability, narrow therapeutic window, the effect of other medications, comorbidity (more than one disease at a time), nonlinear patient dynamics, and time-varying patient dose response characteristics which include bleeding (internal and external). This research aims to develop a framework for an adaptive personalized modeling and control method with minimum clinical patient specific dose response data for optimal drug dosing. The proposed methodology is applied to anemia and warfarin management. It is …

Modeling, Simulation And Control Of Microrobots For The Microfactory., Zhong Yang

Electronic Theses and Dissertations

Future assembly technologies will involve higher levels of automation in order to satisfy increased microscale or nanoscale precision requirements. Traditionally, assembly using a top-down robotic approach has been well-studied and applied to the microelectronics and MEMS industries, but less so in nanotechnology. With the boom of nanotechnology since the 1990s, newly designed products with new materials, coatings, and nanoparticles are gradually entering everyone’s lives, while the industry has grown into a billion-dollar volume worldwide. Traditionally, nanotechnology products are assembled using bottom-up methods, such as self-assembly, rather than top-down robotic assembly. This is due to considerations of volume handling of large …

Power System Dynamic Control And Performance Improvement Based On Reinforcement Learning, Wei Gao

Electronic Theses and Dissertations

This dissertation investigates the feasibility and effectiveness of using Reinforcement Learning (RL) techniques for power system dynamic control, particularly voltage and frequency control. The conventional control strategies used in power systems are complex and time-consuming due to the complicated high-order nonlinearities of the system. RL, which is a type of neural network-based technique, has shown promise in solving these complex problems by fitting any nonlinear system with the proper network structure.

The proposed RL algorithm, called Guided Surrogate Gradient-based Evolution Strategy (GSES) determines the weights of the policy (which generates the action for our control reference signal) without back-propagation process …

Enhancing Traffic Safety In Unpredicted Environments With Integration Of Adas Features With Sensor Fusion In Intelligent Electric Vehicle Platform With Implementation Of Environmental Mapping Technology, David S. Obando Ortegon

Electronic Theses and Dissertations

A major objective on society is to reduce the number of accidents and fatalities on the road for drivers, and pedestrians. Therefore, the automotive engineering field is working on this problem through the development and integration of safety technologies such as advanced driving assistance systems. For this reason, this work was intended to develop and evaluate the performance of different ADAS features and IV technologies under unexpected scenarios. This by the development of safety algorithms applied to the intelligent electric vehicle designed and built in this work, through the use of ADAS sensors based on sensor fusion. Evaluation of AEB, …

Design And Fabrication Of A Force-Displacement Control Mechanism For Bone-Surgical Tool Testing, Kenneth Nwagu

Electronic Theses and Dissertations

This project focuses on the design and fabrication of an experimental setup for orthopedic-tool testing, tailored for a surgical instrumentation company. The multifaceted project encompasses a literature review, conceptual design, prototyping, and rigorous testing, resulting in a versatile control system capable of assessing various orthopedic tools, including bone drills, saws, burrs, and power handpieces.

Orthopedic surgical procedures (which include cutting and/or drilling into bone) often need to be performed on bones for faster recovery. The drilling and cutting process can cause an increase in temperature at the cutting site which can cause bone necrosis. The tools also need to be …