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Full-Text Articles in Computer Engineering

A Robust Platform For Mobile Robotics Teaching And Developing Using Arduino’S Integrated Development Environment (Ide) For Programming The Arduino Mega 2560, Sajjad Alhassan Dec 2022

A Robust Platform For Mobile Robotics Teaching And Developing Using Arduino’S Integrated Development Environment (Ide) For Programming The Arduino Mega 2560, Sajjad Alhassan

Department of Electrical and Computer Engineering: Dissertations, Theses, and Student Research

In light of the rapid pace at which development happens with modern technology, mobile robots play an important role in our daily lives. This is due to their great importance in facilitating the affairs of life in various economic, commercial, industrial, scientific, and many other fields. In this research and project, we have restructured the microcontroller and system for one of the mobile robots (CEENBOT) that was designed by the University of Nebraska and replaced it with an Arduino Mega 2560.

The purpose of using the Arduino Mega 2560 robot is to provide alternative programming for the CEENBOT platform to …


Low Power Multi-Channel Interface For Charge Based Tactile Sensors, Samuel Hansen Dec 2022

Low Power Multi-Channel Interface For Charge Based Tactile Sensors, Samuel Hansen

Department of Electrical and Computer Engineering: Dissertations, Theses, and Student Research

Analog front end electronics are designed in 65 nm CMOS technology to process charge pulses arriving from a tactile sensor array. This is accomplished through the use of charge sensitive amplifiers and discrete time filters with tunable clock signals located in each of the analog front ends. Sensors were emulated using Gaussian pulses during simulation. The digital side of the system uses SAR (successive approximation register) ADCs for sampling of the processed sensor signals.

Adviser: Sina Balkır


A Stacking-Based Misbehavior Detection System In Vehicular Communication Networks, Troy Green Dec 2022

A Stacking-Based Misbehavior Detection System In Vehicular Communication Networks, Troy Green

Department of Electrical and Computer Engineering: Dissertations, Theses, and Student Research

Over the past few decades communication systems for vehicles have continued to advance. Communications between these vehicles can be classified into safety related and non safety related messages. An example of a safety related message would be one vehicle warning others of an icy road it encountered, where a non safety related communication would be a passenger streaming a movie. In either case it's important to secure the communications so that the system continues to behave as expected. In this thesis we propose a Misbehavior Detection System (MDS), which is a system that monitors messages sent between vehicles, and detects …


A Low-Power, Low-Area 10-Bit Sar Adc With Length-Based Capacitive Dac, Zhili Pan Dec 2022

A Low-Power, Low-Area 10-Bit Sar Adc With Length-Based Capacitive Dac, Zhili Pan

Department of Electrical and Computer Engineering: Dissertations, Theses, and Student Research

A 2.5 V single-ended 10-bit successive-approximation-register analog-to-digital converter (SAR ADC) based on the TSMC 65 nm CMOS process is designed with the goal of achieving low power consumption (33.63 pJ/sample) and small area (2874 µm^2 ). It utilizes a novel length-based capacitive digital-to-analog converter (CDAC) layout to achieve low total capacitance for power efficiency, and a custom static asynchronous logic to free the dependence on a high-frequency external clock source. Two test chips have been designed and the problems found through testing the first chip are analyzed. Multiple improved versions of the ADC with minor variations are implemented on the …


Computer Engineering Education, Marilyn Wolf Nov 2022

Computer Engineering Education, Marilyn Wolf

CSE Conference and Workshop Papers

Computer engineering is a rapidly evolving discipline. How should we teach it to our students?

This virtual roundtable on computer engineering education was conducted in summer 2022 over a combination of email and virtual meetings. The panel considered what topics are of importance to the computer engineering curriculum, what distinguishes computer engineering from related disciplines, and how computer engineering concepts should be taught.


Updated Perspectives On The Role Of Biomechanics In Copd: Considerations For The Clinician, Jennifer M. Yentes, Wai-Yan Liu, Kuan Zhang, Eric J. Markvicka, Stephen I. Rennard Oct 2022

Updated Perspectives On The Role Of Biomechanics In Copd: Considerations For The Clinician, Jennifer M. Yentes, Wai-Yan Liu, Kuan Zhang, Eric J. Markvicka, Stephen I. Rennard

Department of Electrical and Computer Engineering: Faculty Publications

Patients with chronic obstructive pulmonary disease (COPD) demonstrate extra-pulmonary functional decline such as an increased prevalence of falls. Biomechanics offers insight into functional decline by examining mechanics of abnormal movement patterns. This review discusses biomechanics of functional outcomes, muscle mechanics, and breathing mechanics in patients with COPD as well as future directions and clinical perspectives. Patients with COPD demonstrate changes in their postural sway during quiet standing compared to controls, and these deficits are exacerbated when sensory information (eg, eyes closed) is manipulated. If standing balance is disrupted with a perturbation, patients with COPD are slower to return to baseline …


Sers Spectroscopy With Machine Learning To Analyze Human Plasma Derived Sevs For Coronary Artery Disease Diagnosis And Prognosis, Xi Huang, Bo Liu, Shenghan Guo, Weihong Guo, Ke Liao, Guoku Hu, Wen Shi, Mitchell Kuss, Michael J. Duryee, Daniel R. Anderson, Yongfeng Lu, Bin Duan Sep 2022

Sers Spectroscopy With Machine Learning To Analyze Human Plasma Derived Sevs For Coronary Artery Disease Diagnosis And Prognosis, Xi Huang, Bo Liu, Shenghan Guo, Weihong Guo, Ke Liao, Guoku Hu, Wen Shi, Mitchell Kuss, Michael J. Duryee, Daniel R. Anderson, Yongfeng Lu, Bin Duan

Department of Electrical and Computer Engineering: Faculty Publications

Coronary artery disease (CAD) is one of the major cardiovascular diseases and represents the leading causes of global mortality. Developing new diagnostic and therapeutic approaches for CAD treatment are critically needed, especially for an early accurate CAD detection and further timely intervention. In this study, we successfully isolated human plasma small extracellular vesicles (sEVs) from four stages of CAD patients, that is, healthy control, stable plaque, non-ST-elevation myocardial infarction, and ST-elevation myocardial infarction. Surface-enhanced Raman scattering (SERS) measurement in conjunction with five machine learning approaches, including Quadratic Discriminant Analysis, Support Vector Machine (SVM), K-Nearest Neighbor, Artificial Neural network, were then …


Sers Spectroscopy With Machine Learning To Analyze Human Plasma Derived Sevs For Coronary Artery Disease Diagnosis And Prognosis, Xi Huang, Bo Liu, Shenghan Guo, Weihong Guo, Ke Liao, Guoku Hu, Wen Shi, Mitchell Kuss, Michael J. Duryee, Daniel R. Anderson, Yongfeng Lu, Bin Duan Sep 2022

Sers Spectroscopy With Machine Learning To Analyze Human Plasma Derived Sevs For Coronary Artery Disease Diagnosis And Prognosis, Xi Huang, Bo Liu, Shenghan Guo, Weihong Guo, Ke Liao, Guoku Hu, Wen Shi, Mitchell Kuss, Michael J. Duryee, Daniel R. Anderson, Yongfeng Lu, Bin Duan

Department of Electrical and Computer Engineering: Faculty Publications

Coronary artery disease (CAD) is one of the major cardiovascular diseases and represents the leading causes of global mortality. Developing new diagnostic and therapeutic approaches for CAD treatment are critically needed, especially for an early accurate CAD detection and further timely intervention. In this study, we successfully isolated human plasma small extracellular vesicles (sEVs) from four stages of CAD patients, that is, healthy control, stable plaque, non-ST-elevation myocardial infarction, and ST-elevation myocardial infarction. Surface-enhanced Raman scattering (SERS) measurement in conjunction with five machine learning approaches, including Quadratic Discriminant Analysis, Support Vector Machine (SVM), K-Nearest Neighbor, Artificial Neural network, were then …


Parasol: Efficient Parallel Synthesis Of Large Model Spaces, Clay Stevens, Hamid Bagheri Sep 2022

Parasol: Efficient Parallel Synthesis Of Large Model Spaces, Clay Stevens, Hamid Bagheri

CSE Conference and Workshop Papers

Formal analysis is an invaluable tool for software engineers, yet state-of-the-art formal analysis techniques suffer from well-known limitations in terms of scalability. In particular, some software design domains—such as tradeoff analysis and security analysis—require systematic exploration of potentially huge model spaces, which further exacerbates the problem. Despite this present and urgent challenge, few techniques exist to support the systematic exploration of large model spaces. This paper introduces Parasol, an approach and accompanying tool suite, to improve the scalability of large-scale formal model space exploration. Parasol presents a novel parallel model space synthesis approach, backed with unsupervised learning to automatically derive …


Nonlinear Strong Coupling By Second-Harmonic Generation Enhancement In Plasmonic Nanopatch Antennas, Bryson Krause, Dhananjay Mishra, Jiyang Chen, Christos Argyropoulos, Thang Hoang Aug 2022

Nonlinear Strong Coupling By Second-Harmonic Generation Enhancement In Plasmonic Nanopatch Antennas, Bryson Krause, Dhananjay Mishra, Jiyang Chen, Christos Argyropoulos, Thang Hoang

Department of Electrical and Computer Engineering: Faculty Publications

Enhanced electromagnetic fields within plasmonic nanocavity mode volumes enable multiple significant effects that lead to applications in both the linear and nonlinear optical regimes. In this work, we demonstrate enhanced second harmonic generation from individual plasmonic nanopatch antennas which are formed by separating silver nanocubes from a smooth gold film using a sub-10 nm zinc oxide spacer layer. When the nanopatch antennas are excited at their fundamental plasmon frequency, a 104-fold increase in the intensity of the second harmonic generation wave is observed. Moreover, by integrating quantum emitters that have an absorption energy at the fundamental frequency, a …


A New Implementation Of Federated Learning For Privacy And Security Enhancement, Xiang Ma, Haijian Sun, Rose Qingyang Hu, Yi Qian Aug 2022

A New Implementation Of Federated Learning For Privacy And Security Enhancement, Xiang Ma, Haijian Sun, Rose Qingyang Hu, Yi Qian

Department of Electrical and Computer Engineering: Faculty Publications

Motivated by the ever-increasing concerns on personal data privacy and the rapidly growing data volume at local clients, federated learning (FL) has emerged as a new machine learning setting. An FL system is comprised of a central parameter server and multiple local clients. It keeps data at local clients and learns a centralized model by sharing the model parameters learned locally. No local data needs to be shared, and privacy can be well protected. Nevertheless, since it is the model instead of the raw data that is shared, the system can be exposed to the poisoning model attacks launched by …


Feature Analysis Of Indus Valley And Dravidian Language Scripts With Similarity Matrices, Sarat Sasank Barla, Sai Surya Sanjay Alamuru, Peter Revesz Aug 2022

Feature Analysis Of Indus Valley And Dravidian Language Scripts With Similarity Matrices, Sarat Sasank Barla, Sai Surya Sanjay Alamuru, Peter Revesz

CSE Conference and Workshop Papers

This paper investigates the similarity between the Indus Valley script and the Kannada, Malayalam, Tamil, and Telugu scripts that are used to write Dravidian languages. The closeness of these scripts is determined by applying a feature analysis of each sign of these scripts and creating similarity matrices that describe the similarity of any pair of signs from two different scripts. The feature list that we use for the analysis of these Dravidian language-related scripts includes six new features beyond the thirteen features that were used for the study of Minoan Linear A and related scripts by Revesz. These new features …


A Novel Testbed For Evaluation Of Operational Technology Communications Protocols And Their On-Device Implementations, Matthew Boeding Aug 2022

A Novel Testbed For Evaluation Of Operational Technology Communications Protocols And Their On-Device Implementations, Matthew Boeding

Department of Electrical and Computer Engineering: Dissertations, Theses, and Student Research

Operational Technology (OT) and Infrastructure Technology (IT) systems are converging with the rapid addition of centralized remote management in OT systems. Previously air-gapped systems are now interconnected through the internet with application-specific protocols. This has led to systems that had limited access points being remotely accessible. In different OT sectors, legacy protocols previously transmitted over serial communication were updated to allow internet communication with legacy devices. New protocols such as IEC-61850 were also introduced for monitoring of different OT resources. The IEC-61850 standard’s Generic Object Oriented Substation Event (GOOSE) protocol outlines the representation and communication of a variety of different …


Femtosecond Laser Surface Processing To Create Self-Organized Micro- And Nano-Scale Features On Composite And Ceramic Materials, Nate Koeppe Aug 2022

Femtosecond Laser Surface Processing To Create Self-Organized Micro- And Nano-Scale Features On Composite And Ceramic Materials, Nate Koeppe

Department of Electrical and Computer Engineering: Dissertations, Theses, and Student Research

Femtosecond laser surface processing (FLSP) is applied to a range of materials in this thesis. The materials studied were a carbon fiber reinforced polymer (CFRP), a thermosetting polymer, silicon nitride (Si3N4), and ceramic alumina. The CFRP is a composite material consisting of a thermosetting polymer and carbon fibers. The CFRP are referred to as a composite and the thermosetting polymer is referred to as a resin in this thesis. Alumina can exist in many different forms. The alumina used is 0.5 mm thick nonporous alumina sheets purchased from McMaster-Carr, and will be referred to as alumina …


Combining Solution Reuse And Bound Tightening For Efficient Analysis Of Evolving Systems, Clay Stevens, Hamid Bagheri Jul 2022

Combining Solution Reuse And Bound Tightening For Efficient Analysis Of Evolving Systems, Clay Stevens, Hamid Bagheri

CSE Conference and Workshop Papers

Software engineers have long employed formal verification to ensure the safety and validity of their system designs. As the system changes—often via predictable, domain-specific operations—their models must also change, requiring system designers to repeatedly execute the same formal verification on similar system models. State-of-the-art formal verification techniques can be expensive at scale, the cost of which is multiplied by repeated analysis. This paper presents a novel analysis technique—implemented in a tool called SoRBoT—which can automatically determine domain-specific optimizations that can dramatically reduce the cost of repeatedly analyzing evolving systems. Different from all prior approaches, which focus on either tightening the …


Influence Of Aluminum Addition On The Laser Powder Bed Fusion Of Copper-Aluminum Mixtures, Nada Kraiem, Loic Constantin, A. Mao, Fei Wang, Bai Cui, Jean-François Silvain, Yongfeng Lu Jul 2022

Influence Of Aluminum Addition On The Laser Powder Bed Fusion Of Copper-Aluminum Mixtures, Nada Kraiem, Loic Constantin, A. Mao, Fei Wang, Bai Cui, Jean-François Silvain, Yongfeng Lu

Department of Electrical and Computer Engineering: Faculty Publications

The high optical reflectivity of copper (Cu) in the near infrared (NIR) domain and its elevated heat dissipation make Cu a challenging metal for laser powder bed fusion (LPBF), even with high energy densities (EDs). In this study, we demonstrated that adding aluminum (Al) powder by as little as 0.75, 1.5, and 3 wt.% substantially enhances Cu processability, leading to denser (up to 98%) and smoother (Ra = 3.3 𝜇m) Cu-Al parts as compared to 95% and 18 𝜇m, respectively, for the parts printed using pure Cu. In addition, this method reduces the ED required by a factor of two …


Asymmetric Control Of Light At The Nanoscale, Christos Argyropoulos Jul 2022

Asymmetric Control Of Light At The Nanoscale, Christos Argyropoulos

Department of Electrical and Computer Engineering: Faculty Publications

Breaking reciprocity at the nanoscale can produce directional formation of images due to the asymmetric nonlinear optical response of subwavelength anisotropic resonators. The self-induced passive non-reciprocity has advantages compared to magnet or time modulation approaches and may impact both classical and quantum photonics.


One-Bit Algorithm Considerations For Sparse Pmcw Radar, Ethan Triplett Jul 2022

One-Bit Algorithm Considerations For Sparse Pmcw Radar, Ethan Triplett

Department of Electrical and Computer Engineering: Dissertations, Theses, and Student Research

Phase Modulated Continuous Wave (PMCW) radar an emerging technology for autonomous cars. It is more flexible than the current frequency modulated systems, offering better detection resolution, interference mitigation, and future development opportunities. The issue preventing PMCW adoption is the need for high sample-rate analog to digital converters (ADCs). Due to device limits, a large increase in cost and power consumption occurs for every added resolution bit for a given sampling rate. This thesis explores radar detection techniques for few-bit and 1-bit ADC measurements. 1-bit quantization typically results in poor amplitude estimation, which can limit detections if the target signals are …


Halide Perovskites Enable Polaritonic Xy Spin Hamiltonian At Room Temperature, Renjie Tao, Kai Peng, Louis Haeberlé, Quanwei Li, Dafei Jin, Graham R. Fleming, Stéphane Kéna-Cohen, Xiang Zhang, Wei Bao Jun 2022

Halide Perovskites Enable Polaritonic Xy Spin Hamiltonian At Room Temperature, Renjie Tao, Kai Peng, Louis Haeberlé, Quanwei Li, Dafei Jin, Graham R. Fleming, Stéphane Kéna-Cohen, Xiang Zhang, Wei Bao

Department of Electrical and Computer Engineering: Faculty Publications

Exciton polaritons, the part-light and part-matter quasiparticles in semiconductor optical cavities, are promising for exploring Bose–Einstein condensation, non-equilibrium many-body physics and analogue simulation at elevated temperatures. However, a room-temperature polaritonic platform on par with the GaAs quantum wells grown by molecular beam epitaxy at low temperatures remains elusive. The operation of such a platform calls for long-lifetime, strongly interacting excitons in a stringent material system with large yet nanoscale-thin geometry and homogeneous properties. Here, we address this challenge by adopting a method based on the solution synthesis of excitonic halide perovskites grown under nanoconfinement. Such nanoconfinement growth facilitates the synthesis …


Rechargeable Multi-Cell Battery, Wei Qiao, Taesic Kim, Liyan Qu May 2022

Rechargeable Multi-Cell Battery, Wei Qiao, Taesic Kim, Liyan Qu

Department of Electrical and Computer Engineering: Faculty Publications

A method for power management of a multi - cell battery includes identifying a desired power value and voltage value , determining a battery voltage value and a battery current value for a battery , determining a number of battery banks from a plurality of battery banks to use for the battery , where each battery bank includes one or more battery cells ( or battery modules ) , checking availability of each of the one or more battery cells ( or battery modules ) , selecting one or more battery banks from the plurality of battery banks , where …


A High-Density Theta Burst Paradigm Enhances The Aftereffects Of Transcranial Magnetic Stimulation: Evidence From Focal Stimulation Of Rat Motor Cortex, Qinglei Meng, Hieu Nguyen, Antonia Vrana, Simone Baldwin, Charlotte Qiong Li, Antonia Giles, Jun Wang, Yihong Yang, Hanbing Lu May 2022

A High-Density Theta Burst Paradigm Enhances The Aftereffects Of Transcranial Magnetic Stimulation: Evidence From Focal Stimulation Of Rat Motor Cortex, Qinglei Meng, Hieu Nguyen, Antonia Vrana, Simone Baldwin, Charlotte Qiong Li, Antonia Giles, Jun Wang, Yihong Yang, Hanbing Lu

Department of Electrical and Computer Engineering: Faculty Publications

Background: Theta burst stimulation (TBS) is an efficient noninvasive neuromodulation paradigm that has been widely adopted, clinically. However, the efficacy of TBS treatment remains similarly modest as conventional 10 Hz repetitive transcranial magnetic stimulation (rTMS).

Objective/hypothesis: To develop a new TBS paradigm that enhances the effects of TMS administration while maintaining high time-efficiency.

Methods: We describe here a new TMS paradigm, named High-Density Theta Burst Stimulation (hdTBS). This paradigm delivers up to 6 pulses per burst, as opposed to only 3 in conventional TBS, while maintaining the inter-burst interval of 200 ms (or 5 Hz) - a …


Design Of Hardware To Aid Smartphone-Based Oscilloscope App, Riddock Moran May 2022

Design Of Hardware To Aid Smartphone-Based Oscilloscope App, Riddock Moran

Honors Theses

A smartphone-based oscilloscope improves on traditional lab oscilloscopes in accessibility and portability but faces several performance limitations compared to traditional oscilloscopes. Among these, an oscilloscope app that uses the phone’s audio to read voltage signals will have a sampling rate and voltage bottlenecked by the capabilities of the audio codec, which will rarely exceed a rate of 48 kHz and 1 volt, respectively. Additionally, smartphones lack the ability to read line-in audio, allowing only one channel input through the microphone. Direct connections to an audio source may not be possible due to requiring an audio jack connection, and different poles …


Identification Of Orthologous Gene Groups Using Machine Learning, Dillon Burgess Apr 2022

Identification Of Orthologous Gene Groups Using Machine Learning, Dillon Burgess

Department of Electrical and Computer Engineering: Dissertations, Theses, and Student Research

Identification of genes that show similarity between different organisms, a.k.a orthologous genes, is an open problem in computational biology. The purpose of this thesis is to create an algorithm to group orthologous genes using machine learning. Following an optimization step to find the best characterization based on training data, we represented sequences of genes or proteins with kmer vectors. These kmer vectors were then clustered into orthologous groups using hierarchical clustering. We optimized the clustering phase with the same training data for the method and parameter selection. Our results indicated that use of protein sequences with k=2 and scaling the …


Learning Domain Invariant Information To Enhance Presentation Attack Detection In Visible Face Recognition Systems, Jennifer Hamblin Apr 2022

Learning Domain Invariant Information To Enhance Presentation Attack Detection In Visible Face Recognition Systems, Jennifer Hamblin

Department of Electrical and Computer Engineering: Dissertations, Theses, and Student Research

Face signatures, including size, shape, texture, skin tone, eye color, appearance, and scars/marks, are widely used as discriminative, biometric information for access control. Despite recent advancements in facial recognition systems, presentation attacks on facial recognition systems have become increasingly sophisticated. The ability to detect presentation attacks or spoofing attempts is a pressing concern for the integrity, security, and trust of facial recognition systems. Multi-spectral imaging has been previously introduced as a way to improve presentation attack detection by utilizing sensors that are sensitive to different regions of the electromagnetic spectrum (e.g., visible, near infrared, long-wave infrared). Although multi-spectral presentation attack …


Queueing Theory Model Of Pentose Phosphate Pathway, Sylwester M. Kloska, Krzysztof Pałczyński, Tomasz Marciniak, Tomasz Talaśka, Marissa Miller, Beata J. Wysocki, Paul H. Davis, Tadeusz A. Wysocki Mar 2022

Queueing Theory Model Of Pentose Phosphate Pathway, Sylwester M. Kloska, Krzysztof Pałczyński, Tomasz Marciniak, Tomasz Talaśka, Marissa Miller, Beata J. Wysocki, Paul H. Davis, Tadeusz A. Wysocki

Department of Electrical and Computer Engineering: Faculty Publications

Due to its role in maintaining the proper functioning of the cell, the pentose phosphate pathway (PPP) is one of the most important metabolic pathways. It is responsible for regulating the concentration of simple sugars and provides precursors for the synthesis of amino acids and nucleotides. In addition, it plays a critical role in maintaining an adequate level of NADPH, which is necessary for the cell to fight oxidative stress. These reasons prompted the authors to develop a computational model, based on queueing theory, capable of simulating changes in PPP metabolites’ concentrations. The model has been validated with empirical data …


A Precise Dispenser Design For Canine Cognition Research, Walker Arce, Jeffrey R. Stevens Feb 2022

A Precise Dispenser Design For Canine Cognition Research, Walker Arce, Jeffrey R. Stevens

Department of Electrical and Computer Engineering: Faculty Publications

Some forms of canine cognition research require a dispenser that can accurately dispense precise quantities of treats. When using off-the-shelf or retrofitted dispensers, there is no guarantee that a precise number of treats will be dispensed. Often, they will over-dispense treats, which may not be acceptable for some tasks. Here we describe a 3D-printed precise treat dispenser with a 59-treat capacity driven by a stepper motor drive and controlled by an integrated Raspberry Pi. The dispenser can be built for less than 200 USD and is fully 3D printable. While off-the-shelf dispensers can result in an error rate of 20–30%, …


Nanomechanical Resonators: Toward Atomic Scale, Bo Xu, Pengcheng Zhang, Jiankai Zhu, Zuheng Liu, Alexander Eichler, Xu-Qian Zheng, Jaesung Lee, Aneesh Dash, Swapnil More, Song Wu, Yanan Yanan, Hao Jia, Akshay Naik, Adrian Bachtold, Rui Yang, Philip X.-L. Feng, Zenghui Wang Jan 2022

Nanomechanical Resonators: Toward Atomic Scale, Bo Xu, Pengcheng Zhang, Jiankai Zhu, Zuheng Liu, Alexander Eichler, Xu-Qian Zheng, Jaesung Lee, Aneesh Dash, Swapnil More, Song Wu, Yanan Yanan, Hao Jia, Akshay Naik, Adrian Bachtold, Rui Yang, Philip X.-L. Feng, Zenghui Wang

Department of Electrical and Computer Engineering: Faculty Publications

The quest for realizing and manipulating ever smaller man-made movable structures and dynamical machines has spurred tremendous endeavors, led to important discoveries, and inspired researchers to venture to new grounds. Scientific feats and technological milestones of miniaturization of mechanical structures have been widely accomplished by advances in machining and sculpturing ever shrinking features out of bulk materials such as silicon. With the flourishing multidisciplinary field of low-dimensional nanomaterials, including one-dimensional (1D) nanowires/nanotubes, and two-dimensional (2D) atomic layers such as graphene/phosphorene, growing interests and sustained efforts have been devoted to creating mechanical devices toward the ultimate limit of miniaturization— genuinely down …


Serum Protein Signatures Using Aptamer-Based Proteomics For Minimal Change Disease And Membranous Nephropathy, Daniel A. Muruve, Hanna Debiec, Simon T. Dillon, Xuesong Gu, Emmanuelle Plaisier, Handan Can, Hasan H. Otu, Towia A. Libermann, Pierre Ronco Jan 2022

Serum Protein Signatures Using Aptamer-Based Proteomics For Minimal Change Disease And Membranous Nephropathy, Daniel A. Muruve, Hanna Debiec, Simon T. Dillon, Xuesong Gu, Emmanuelle Plaisier, Handan Can, Hasan H. Otu, Towia A. Libermann, Pierre Ronco

Department of Electrical and Computer Engineering: Faculty Publications

Introduction: Minimal change disease (MCD) and membranous nephropathy (MN) are glomerular diseases (glomerulonephritis [GN]) that present with the nephrotic syndrome. Although circulating PLA2R antibodies have been validated as a biomarker for MN, the diagnosis of MCD and PLA2R-negative MN still relies on the results of kidney biopsy or empirical corticosteroids in children. We aimed to identify serum protein biomarker signatures associated with MCD and MN pathogenesis using aptamer-based proteomics.

Methods: Quantitative SOMAscan proteomics was applied to the serum of adult patients with MCD (n = 15) and MN(n = 37) and healthy controls (n = …


Data Science Applied To Discover Ancient Minoan-Indus Valley Trade Routes Implied By Commonweight Measures, Peter Revesz Jan 2022

Data Science Applied To Discover Ancient Minoan-Indus Valley Trade Routes Implied By Commonweight Measures, Peter Revesz

CSE Conference and Workshop Papers

This paper applies data mining of weight measures to discover possible long-distance trade routes among Bronze Age civilizations from the Mediterranean area to India. As a result, a new northern route via the Black Sea is discovered between the Minoan and the Indus Valley civilizations. This discovery enhances the growing set of evidence for a strong and vibrant connection among Bronze Age civilizations.