Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Biomaterials
The Role Of Surface Characteristics In The Initial Adhesion Of Human Bone-Derived Cells On Ceramics, H. Zreiqat, O. C. Standard, T. Gengenbach, J. G. Steele, C. R. Howlett
The Role Of Surface Characteristics In The Initial Adhesion Of Human Bone-Derived Cells On Ceramics, H. Zreiqat, O. C. Standard, T. Gengenbach, J. G. Steele, C. R. Howlett
Cells and Materials
The tissue/biomaterial interactions of three biomaterials of potential use in bone implants were studied in vitro. The mechanism of cell adherence to various ceramic substrata has been investigated by measurement of short term (90 minutes) cell attachment and spreading rate. We have determined the effect of two serum glycoproteins, fibronectin and vitronectin, on the adhesion of human bone derived cells (HBD-cells) cultured on three different types of ceramics {alumina (Al2O3), hydroxyapatite (HAP) and yttria-doped tetragonal zirconia polycrystal (Y-TZP)} . The attachment of HBD-cells to alumina and hydroxyapatite was approximately 60% of that to Y-TZP. Furthermore, …