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Articles 1 - 3 of 3
Full-Text Articles in Biomaterials
Biodegradable Nano-Hybrid Polymer Composite Networks For Regulating Cellular Behavior, Charles Henley Sprague
Biodegradable Nano-Hybrid Polymer Composite Networks For Regulating Cellular Behavior, Charles Henley Sprague
Masters Theses
Photo-crosslinkable polymeric biomaterials have emerged in the field of biomedical research to promote tissue regeneration. For example, scaffolds that can be crosslinked and hardened in situ have been known to make suitable implant alternatives. Since injectable and photo-crosslinkable biomaterials offer the advantage of being minimally invasive, they have emerged to compete with autografts, a current highly invasive method to repair diseased tissue. A series of novel photo-crosslinkable, injectable, and biodegradable nano-hybrid polymers consisting of poly(ε-caprolactone fumarate) (PCLF) and polyhedral oligomeric silsesquioxane (POSS) has been synthesized in our laboratory via polycondensation. To engineer the material properties of the nano-hybrid networks, varied …
Engineering The “Pluripotency” Of Zr-Based Bulk Metallic Glasses As Biomedical Materials, Lu Huang
Engineering The “Pluripotency” Of Zr-Based Bulk Metallic Glasses As Biomedical Materials, Lu Huang
Doctoral Dissertations
Bulk metallic glasses (BMGs) are a family of novel alloys with amorphous microstructures. The combination of their excellent mechanical properties, good chemical stability, high thermal formability, and general biocompatibility has brought up new opportunities for biomaterials. Research in this dissertation was focused on exploring multiple biomedical functionalities of Zr-based BMGs over a wide spectrum, combining materials and biological characterizations, through experimental and computational approaches. Four distinct yet interconnected tasks were endeavored, involving inflammation, hard-tissue implant, soft-tissue prosthesis, and pathogenic infection.
The inflammation that can be potentially triggered by Zr-based BMGs was investigated using macrophages. Lower level or comparable macrophage activations …
Doping Of Fluorchlorozirconate And Borate-Silica Glass Ceramics For Medical Imaging And Fast Neutron Scintillation, Julie Elizabeth Swafford
Doping Of Fluorchlorozirconate And Borate-Silica Glass Ceramics For Medical Imaging And Fast Neutron Scintillation, Julie Elizabeth Swafford
Masters Theses
Borate silica glass ceramics were produced for neutron scintillation. The Glass ceramics were doped with europium fluoride [EuF2] and cerium chloride [CeCl3]. Isotopic lithium fluoride [6LiF] and boron oxide [10B2O3] were used in most samples while non-isotopic lithium fluoride [LiF] and boron oxide [ B2O3] were used in the rest. When exposed to a neutron beam, samples doped with europium fluoride [EuF2] scintillated while samples doped with cerium chloride [CeCl3] did not. This contradicts current literature on fast scintillation. What …