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Full-Text Articles in Biomaterials
Developing Aligned Nerve Scaffolds In A 3d Type-I Collagen Gel, Gabriel David
Developing Aligned Nerve Scaffolds In A 3d Type-I Collagen Gel, Gabriel David
Biomedical Engineering Undergraduate Honors Theses
Despite significant progress in the field of peripheral nerve repair, clinical success is still limited, leaving millions to suffer from peripheral neuropathy with billions spent every year for treatment. Nerve repair methods that are capable of maximizing the regenerative properties of peripheral nerves are greatly desired in the field of medical science. This research aims to fill the gap between modern methods and the future of nerve repair by creating type-I collagen scaffolds with aligned degradation pores that will assist and nurture nerves growing through them. This is achieved by incorporating adipose stem cells into type-I collagen hydrogels and aligning …
Design Of Microporous Membranes For The Development Of Brain-On-Chip Devices, Andre Figueroa Milla
Design Of Microporous Membranes For The Development Of Brain-On-Chip Devices, Andre Figueroa Milla
Biomedical Engineering Undergraduate Honors Theses
Traumatic brain injuries (TBIs) are a major global health concern that have an economic impact of $60 billion in the United States in related costs annually. Developing drugs for TBI treatment is an approach that currently faces limitations involving the permeability of the blood-brain barrier (BBB). The BBB naturally limits molecules from reaching the brain as a protective mechanism against disease, acting as a barrier during drug delivery. Understanding the BBB mechanically and chemically following a TBI could potentially assist future studies to alleviate the symptoms and long-term effects of TBI by pharmaceuticals. The Mechanobiology and Soft Materials Laboratory (MSML) …