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Full-Text Articles in Biomaterials
Degradable Zinc Material Characteristics And Its Influence On Biocompatibility In An In-Vivo Murine Model, Roger J. Guillory Ii
Degradable Zinc Material Characteristics And Its Influence On Biocompatibility In An In-Vivo Murine Model, Roger J. Guillory Ii
Dissertations, Master's Theses and Master's Reports
Biodegradable stents based on zinc have been under development since their introduction in 2013. While metallic zinc is highly ductile, it unfortunately lacks the mechanical strength required for arterial stents. This has led to the development of an abundance of novel zinc-based materials, with the aim of improving the mechanical strength without sacrificing too much ductility. Although these materials are intended to function and slowly degrade within an artery, most zinc-based materials have been developed without deep consideration for their biological effects.
The present work explores the biological effects elicited by zinc-based materials implanted within the arterial system. The biological …