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Hydrolytic Degradation Study Of Polyphosphazene-Plga Blends, Riley Blumenfield
Hydrolytic Degradation Study Of Polyphosphazene-Plga Blends, Riley Blumenfield
Honors Scholar Theses
The synthesis and in vitro degradation analysis of thin films of poly[(glycineethylglycinato)75(phenylphenoxy)25phosphazene] (PNGEG75PhPh25) and poly[(ethylphenylalanato)25(glycine- ethylglycinato)75phosphazene] (PNEPA25GEG75) blended with poly(lactic-co-glycolic acid) (PLGA) was conducted to determine the blends’ potential for use as scaffolding materials for tissue regeneration applications. The samples were synthesized with glycylglycine ethyl ester (GEG) acting as the primary substituent side group, with cosubstitution by phenylphenol (PhPh) and phenylalanine ethyl ester (EPA) to make the final product [1]. Blends of 25% polyphosphazene, 75% PLGA and 50% polyphosphazene, 50% PLGA were …