Biomaterials Commons^™

Three-Dimensional Confocal Microscopy Indentation Method For Hydrogel Elasticity Measurement, Donghee Lee, Md Mahmudur Rahman, You Zhou, Sangjin Ryu

Md Mahmudur Rahman

No abstract provided.

Application Of Limited Mixing In The Hele-Shaw Geometry In Fabrication Of Janus Hydrogels, Md Mahmudur Rahman

Md Mahmudur Rahman

It is widely accepted that cells behave differently responding to the stiffness of their extracellular matrix (ECM). Such observations were made by culturing cells on hydrogel substrates of tunable stiffness. However, it was recently proposed that cells may sense how strongly they are tethered to ECM, not the local stiffness of ECM. To investigate both hypotheses, we developed a method to fabricate Janus polyacrylamide (PAAM) gels. We squeeze two drops of different concentrations in the Hele-Shaw geometry to generate radial Stokes flow. When the drops coalesce, limited mixing occurs at the interface due to the narrow confinement, and diffusion normal …

Is The 3d Sound-Induced Motion Of The Tympanic Membrane Consistent With Thin-Shell Theory?, Morteza Khaleghi, Cosme Furlong, Jeffrey Tao Cheng, John J. Rosowski

Morteza Khaleghi

The acousto-mechanical-transformer behavior of the tympanic membrane (TM) is determined by its shape and mechanical properties. Holographic studies of 1D vibrations of the TM have been reported by several groups; however, 3D

measurements of TM displacement are few. In this study, we will use full-field-of-view holographic techniques to near simultaneously measure the shape and 3D sound-induced

displacement of cadaveric TMs.

The geometrical constraints imposed by the ear canal make 3D measures of TM displacement in intact ears difficult. However, we can, even in such a confined geometry, measure both a 1D component of sound-induced displacement and

the shape of the …