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Full-Text Articles in Biomedical Engineering and Bioengineering

Is First-Order Vector Autoregressive Model Optimal For Fmri Data?, Chee-Ming Ting, Abd-Krim Seghouane, Muhammad Usman Khalid, Sh-Hussain Salleh Dec 2014

Is First-Order Vector Autoregressive Model Optimal For Fmri Data?, Chee-Ming Ting, Abd-Krim Seghouane, Muhammad Usman Khalid, Sh-Hussain Salleh

Chee-Ming Ting

We consider the problem of selecting the optimal orders of vector autoregressive (VAR) models for fMRI data. Many previous studies used model-order of one and ignored that it may vary considerably across datasets depending on different data dimensions, subjects, tasks and experimental designs. Besides, the classical information criteria (IC) used, e.g. the Akaike IC (AIC) are biased and inappropriate for the high-dimensional fMRI data typically with small sample size. We examine the mixed results on the optimal VAR orders for fMRI, especially the validity of the order-one hypothesis by a comprehensive evaluation using different model selection criteria, over three typical …


Estimating Effective Connectivity From Fmri Data Using Factor-Based Subspace Autoregressive Models, Chee-Ming Ting Phd, Abd-Krim Seghouane Phd, Sh-Hussain Salleh Phd, Alias M. Noor Phd Oct 2014

Estimating Effective Connectivity From Fmri Data Using Factor-Based Subspace Autoregressive Models, Chee-Ming Ting Phd, Abd-Krim Seghouane Phd, Sh-Hussain Salleh Phd, Alias M. Noor Phd

Chee-Ming Ting

We consider the problem of identifying large-scale effective connectivity of brain networks from fMRI data. Standard vector autoregressive (VAR) models fail to estimate reliably networks with large number of nodes. We propose a new method based on factor modeling for reliable and efficient high-dimensional VAR analysis of large networks. We develop a subspace VAR (SVAR) model from a factor model (FM), where observations are driven by a lower-dimensional subspace of common latent factors with an AR dynamics. We consider two variants of principal components (PC) methods that provide consistent estimates for the FM hence the implied SVAR model, even of …


Estimation Of High-Dimensional Brain Connectivity From Fmri Data Using Factor Modeling, Chee-Ming Ting Phd, Abd-Krim Seghouane, Sh-Hussain Salleh, Alias M. Noor Jun 2014

Estimation Of High-Dimensional Brain Connectivity From Fmri Data Using Factor Modeling, Chee-Ming Ting Phd, Abd-Krim Seghouane, Sh-Hussain Salleh, Alias M. Noor

Chee-Ming Ting

We consider identifying effective connectivity of brain networks from fMRI time series. The standard vector autoregressive (VAR) models fail to give reliable network estimates, typically involving very large number of nodes. This paper adopts a dimensionality reduction approach based on factor modeling, to enable effective and efficient high-dimensional VAR analysis of large network connectivity. We derive a subspace VAR (SVAR) model from the factor model (FM) in which the observations are driven by a lower dimensional subspace of common latent factors, following an autoregressive dynamics. We consider the principal components (PC) method which can produce consistent estimators for the FM, …


Estimating Dynamic Cortical Connectivity From Motor Imagery Eeg Using Kalman Smoother & Em Algorithm, S. Balqis Samdin, Chee-Ming Ting Phd, Sh-Hussain Salleh, Mahyar Hamedi, Alias Mohd Noor Jun 2014

Estimating Dynamic Cortical Connectivity From Motor Imagery Eeg Using Kalman Smoother & Em Algorithm, S. Balqis Samdin, Chee-Ming Ting Phd, Sh-Hussain Salleh, Mahyar Hamedi, Alias Mohd Noor

Chee-Ming Ting

This paper considers identifying effective cortical connectivity from scalp EEG. Recent studies use time-varying multivariate autoregressive (TV-MAR) models to better describe the changing connectivity between cortical regions where the TV coefficients are estimated by Kalman filter (KF) within a state-space framework. We extend this approach by incorporating Kalman smoothing (KS) to improve the KF estimates, and the expectation-maximization (EM) algorithm to infer the unknown model parameters from EEG. We also consider solving the volume conduction problem by modeling the induced instantaneous correlations using a full noise covariate. Simulation results show the superiority of KS in tracking the coefficient changes. We …