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Biomedical Engineering and Bioengineering Commons™
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Full-Text Articles in Biomedical Engineering and Bioengineering
A Case Study: Data Management In Biomedical Engineering, Glenn Gaudette, Donna Kafel
A Case Study: Data Management In Biomedical Engineering, Glenn Gaudette, Donna Kafel
Glenn R. Gaudette
In a biomedical engineering lab at Worcester Polytechnic Institute, co-author Dr. Glenn R. Gaudette and his research team are investigating the effects of stem cell therapy on the regeneration of function in damaged cardiac tissue in laboratory rats. Each instance of stem cell experimentation on a rat yields hundreds of data sets that must be carefully captured, documented and securely stored so that the data will be easily accessed and retrieved for papers, reports, further research, and validation of findings, while meeting NIH guidelines for data sharing. After a brief introduction to the bioengineering field and stem cell research, this …
Characterization Of Motor Adaptation And Limb Posture Regulation During Arm Reaching Movements Following Stroke, Robert Scheidt, Tina Stoeckmann
Characterization Of Motor Adaptation And Limb Posture Regulation During Arm Reaching Movements Following Stroke, Robert Scheidt, Tina Stoeckmann
Robert Scheidt
Whether attempting to pour water into a handheld glass, or simply trying to hold a young child's hand, many activities of daily living require interaction with unpredictable or uncertain mechanical environments. Here we describe a systems identification study that used a planar manipulandum to characterize how hemiparetic stroke survivors adapt reaching movements to novel mechanical environments. By analyzing trial-by-trial variations in hand path kinematics, we found that stroke survivors are less likely than neurologically-intact subjects to adjust motor commands for upcoming movements based on hand trajectory errors experienced on previous trials. This ability is most significantly compromised in subjects with …