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Full-Text Articles in Biomedical Engineering and Bioengineering
Three-Dimensional Microfluidic Tumor Vascular Model For Investigating Breast Cancer Metastasis, Anastasiia Vasiukhina, Brian H. Jun, Luis Solorio, Pavlos P. Vlachos
Three-Dimensional Microfluidic Tumor Vascular Model For Investigating Breast Cancer Metastasis, Anastasiia Vasiukhina, Brian H. Jun, Luis Solorio, Pavlos P. Vlachos
The Summer Undergraduate Research Fellowship (SURF) Symposium
Metastasis is one of the primary reasons for the high mortality rates in female patients diagnosed with breast cancer. It involves the migration of cancer cells into the circulatory system allowing for the dissemination of cancer cells in distal tissues. Understanding the major processes that occur in cells and tissues during metastasis can help improve currently existing therapeutic methods. In order to understand such mechanisms, developing physiologically relevant tissue models is crucial. Advancements in microfluidics have led to the fabrication of 3D culture models with shear stress gradients and flow control that can recapitulate aspects of the tumor microenvironment in …
Finite Element Analysis (Fea) Of The Taper-Trunnion Interface In A Metal On Metal Hip Implant, Kyle M. Bradley, Timothy L. Norman, Thomas K. Fehring
Finite Element Analysis (Fea) Of The Taper-Trunnion Interface In A Metal On Metal Hip Implant, Kyle M. Bradley, Timothy L. Norman, Thomas K. Fehring
The Research and Scholarship Symposium (2013-2019)
Metal on metal total hip replacements are a common procedure in which the hip joint is replaced with a metal stem, a metal femoral head and a metal socket, usually made of titanium or cobalt chromium. The stem has a tapered region (trunnion) where the femoral head is impacted onto. This creates what is known as the taper-trunnion interface within a hip implant. However, these hip implants seem to be very susceptible to fretting corrosion, where the corrosive fluid environment of the body accelerates the process of wear between two contact surfaces. Previous research has suggested that the design parameters …
Design Of Tkr Tibial Insert For Bowlegged Gait, Michael R. Gardner, Nathan A. Hanbury, Joel D. Hutchison, Dana C. Madsen, Joel D. Slabach, Kyle M. Bradley, Timothy L. Norman, J. D. Blaha
Design Of Tkr Tibial Insert For Bowlegged Gait, Michael R. Gardner, Nathan A. Hanbury, Joel D. Hutchison, Dana C. Madsen, Joel D. Slabach, Kyle M. Bradley, Timothy L. Norman, J. D. Blaha
The Research and Scholarship Symposium (2013-2019)
One of the causes associated with total knee replacement (TKR) surgery is abnormal gait. In these gait cases, however, the TKR does not solve the ultimate issue because abnormal gait still occurs, and similar excessive forces still occur on the knee. It is likely that the TKR will experience accelerated wear, and the individual may have to undergo a second TKR sometime in the future. For our purposes, bowleggedness is either the external rotation of the hip or excessive varus of the knee. It was hypothesized that the inability to internally rotate the hip increases adduction moment and medial compartment …