Open Access. Powered by Scholars. Published by Universities.®
Biomedical Engineering and Bioengineering Commons™
Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Biomedical Engineering and Bioengineering
3d Printed Force Transducers For In-Vitro Mitral Valve Chordae Tendineae Force Measurements, Hayley Chandler
3d Printed Force Transducers For In-Vitro Mitral Valve Chordae Tendineae Force Measurements, Hayley Chandler
Biomedical Engineering Undergraduate Honors Theses
Mitral valve surgery is incredibly prevalent in the United States with more than 40,000 mitral valve surgical procedures annually. Improving the imaging techniques used to diagnose these cases requires validation of 3D models through experimental data such as mechanical properties of the tissue. An essential part of this process for the mitral valve is measuring the force experienced by chordae tendineae. This has been achieved with brass force transducers but using a 3D printed design can have many benefits. In this study, 3D printed miniature c-shaped force transducers comparable to previous metal models were designed and created using Solidworks 2016. …
Increasing Drug Delivery Efficacy Of Drug-Coated Balloons, Alexander Galan, Eric Bidinger, Franco Godoy, Shrusti Patel
Increasing Drug Delivery Efficacy Of Drug-Coated Balloons, Alexander Galan, Eric Bidinger, Franco Godoy, Shrusti Patel
Senior Theses
Peripheral artery disease (PAD), the narrowing of peripheral arteries located in areas such as the arms and legs, is a common disease that affects 12% to 20% of people over 65. Numerous therapies have been developed to treat PAD, the most recent technology being drug-coated balloons. Drug-coated balloons release drugs, such as Paclitaxel (PTX), into the arterial wall during balloon angioplasty to locally treat PAD. Current levels of drug transfer from the balloon to the vascular endothelium are at a low 10%-18%. Our Biomedical Engineering Senior Design project aims to increase drug delivery of drug-coated balloons by manipulating the clinically-controllable …