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Biomedical Engineering and Bioengineering Commons™
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Full-Text Articles in Biomedical Engineering and Bioengineering
An Application Of M-Matrices To Preserve Bounded Positive Solutions To The Evolution Equations Of Biofilm Models, Richard S. Landry Jr.
An Application Of M-Matrices To Preserve Bounded Positive Solutions To The Evolution Equations Of Biofilm Models, Richard S. Landry Jr.
University of New Orleans Theses and Dissertations
In this work, we design a linear, two step implicit finite difference method to approximate the solutions of a biological system that describes the interaction between a microbial colony and a surrounding substrate. Three separate models are analyzed, all of which can be described as systems of partial differential equations (PDE)s with nonlinear diffusion and reaction, where the biological colony grows and decays based on the substrate bioavailability. The systems under investigation are all complex models describing the dynamics of biological films. In view of the difficulties to calculate analytical solutions of the models, we design here a numerical technique …
The Effect Of Surface Roughness Modifications And Chitosan Surface Coatings On Biofilm Formation For Prevention Of Orthopaedic Infections, Nathan Dewayne Smith
The Effect Of Surface Roughness Modifications And Chitosan Surface Coatings On Biofilm Formation For Prevention Of Orthopaedic Infections, Nathan Dewayne Smith
All Theses
Infections have been reported to occur in up to 91% of patients after orthopaedic procedures. Many of these infections are caused by bacterial biofilm growth on the surface of the implanted device. Surface modifications of fracture fixation implants have been taken into consideration in order to reduce infection rates and improve clinical results in orthopaedic procedures. Effective surface treatments will also reduce the need for antibiotics and prevent formation of drug-resistant bacteria. Titanium alloy sample discs (N=144) were prepared with six surface roughness treatments through polishing as well as with four different concentrations of chitosan through spin coating. In vitro …