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Biomedical Engineering and Bioengineering Commons™
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Full-Text Articles in Biomedical Engineering and Bioengineering
The Prospects Of Zinc As A Structural Material For Biodegradable Implants—A Review Paper, Galit Katarivas Levy, Jeremy Goldman, Eli Aghion
The Prospects Of Zinc As A Structural Material For Biodegradable Implants—A Review Paper, Galit Katarivas Levy, Jeremy Goldman, Eli Aghion
Michigan Tech Publications
In the last decade, iron and magnesium, both pure and alloyed, have been extensively studied as potential biodegradable metals for medical applications. However, broad experience with these material systems has uncovered critical limitations in terms of their suitability for clinical applications. Recently, zinc and zinc-based alloys have been proposed as new additions to the list of degradable metals and as promising alternatives to magnesium and iron. The main byproduct of zinc metal corrosion, Zn2+, is highly regulated within physiological systems and plays a critical role in numerous fundamental cellular processes. Zn2+ released from an implant may suppress …
Effects Of Short Term Hypoxia-Preconditioning On Glial Phenotype Induction Of Human Mesenchymal Stem Cells, Zichen Qian, Qi Xing, Corey Fase, Kyle Jansen, Feng Zhao
Effects Of Short Term Hypoxia-Preconditioning On Glial Phenotype Induction Of Human Mesenchymal Stem Cells, Zichen Qian, Qi Xing, Corey Fase, Kyle Jansen, Feng Zhao
Michigan Tech Publications
Development of successful clinical treatments for peripheral nerve injury is limited due to the complications behind neural physiology. Human mesenchymal stem cells (hMSCs) have the ability to directly promote tissue repair and protect cells at the injury site. Studies have shown that hMSCs can be transplanted to improve nerve regeneration. Hypoxic culture condition has been proven to maintain the stemness of hMSCs for later differentiation. In this study, we investigated the effects of low oxygen (O2) (2% and 5% O2) pre-treatment and initial seeding density (500, 1000, and 2000 cells/cm2) on glial protein expression …