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Full-Text Articles in Biomedical Engineering and Bioengineering

Identification Of Hemodynamically Optimal Coronary Stent Designs Based On Vessel Caliber, Timothy J. Gundert, Alison L. Marsden, Weiguang Yang, David S. Marks, John F. Ladisa Jul 2012

Identification Of Hemodynamically Optimal Coronary Stent Designs Based On Vessel Caliber, Timothy J. Gundert, Alison L. Marsden, Weiguang Yang, David S. Marks, John F. Ladisa

Biomedical Engineering Faculty Research and Publications

Coronary stent design influences local patterns of wall shear stress (WSS) that are associated with neointimal growth, restenosis, and the endothelialization of stent struts. The number of circumferentially repeating crowns NC for a given stent de- sign is often modified depending on the target vessel caliber, but the hemodynamic implications of altering NC have not previously been studied. In this investigation, we analyzed the relationship between vessel diameter and the hemodynamically optimal NC using a derivative-free optimization algorithm coupled with computational fluid dynamics. The algorithm computed the optimal vessel diameter, defined as minimizing the area of stent-induced …


Feasibility Analysis Of Estrification Systems With Entrainers, Kang Wook Lee Jan 2012

Feasibility Analysis Of Estrification Systems With Entrainers, Kang Wook Lee

Dissertations and Theses

(Ethyl Acetate) and IPA (Isopropyl Acetate) production systems are studied in terms of the feasibility analysis. It is not feasible to retrieve pure products by a simple reactive distillation for IPA production system because CCR (Critical Composition Region) covers the entire desired binary edge for IPA system. On the other hand, even though CCR does not cover the entire desired binary edge of the EA system completely, internal reflux ratio (IRR) analysis does not allow the production of the pure product via reactive distillation for EA production system. To overcome the restraints, external entrainers are utilized to take advantage of …