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Biomedical Engineering and Bioengineering Commons

Open Access. Powered by Scholars. Published by Universities.®

2012

Clemson University

All Theses

Dental Pulp

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Effects Of Different Microenvironmental Conditions On The Growth And Differentiation Of Dental Pulp Stem Cells, Matthew Cupelli May 2012

Effects Of Different Microenvironmental Conditions On The Growth And Differentiation Of Dental Pulp Stem Cells, Matthew Cupelli

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Human teeth are very complex structures that are susceptible to many different pathologies due to poor dental health. Currently, there are many restorative methods to reestablish some of the function that teeth have, but the materials used in these methods all have drawbacks and cannot fully mimic the native teeth. Tissue engineering research groups have begun to explore regenerating bone or dental tissue using mesenchymal stem cells derived from the bone marrow. However, our group focuses on regenerating dental tissues using multipotent stem cells from dental pulp.
Dental pulp stem cells (DPSCs) have shown similarities to bone marrow stem cells …