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Full-Text Articles in Biomedical Engineering and Bioengineering
Left Ventricular Assist Devices: Engineering Design Considerations, Marwan A. Simaan, Eduardo Divo, George Faragallah, Yu Wang
Left Ventricular Assist Devices: Engineering Design Considerations, Marwan A. Simaan, Eduardo Divo, George Faragallah, Yu Wang
Publications
Patients with end-stage congestive heart failure awaiting heart transplantation often wait long periods of time (300 days or more on the average) before a suitable donor heart becomes available. The medical community has placed increased emphasis on the use of Left Ventricular Assist Devices or LVADs that can substitute for, or enhance, the function of the natural heart while the patient is waiting for the heart transplant (Poirier, 1997; Frazier & Myers, 1999). Essentially, a rotary LVAD is a pump that operates continuously directing blood from the left ventricle into the aorta by avoiding the aortic valve. Generally speaking, the …
In Vitro Validation Of Finite-Element Model Of Aaa Hemodynamics Incorporating Realistic Outlet Boundary Conditions, Ethan Kung, Andrea S. Les, Francisco Medina, Ryan B. Wicker, Michael V. Mcconnell, Charles A. Taylor
In Vitro Validation Of Finite-Element Model Of Aaa Hemodynamics Incorporating Realistic Outlet Boundary Conditions, Ethan Kung, Andrea S. Les, Francisco Medina, Ryan B. Wicker, Michael V. Mcconnell, Charles A. Taylor
Publications
The purpose of this study is to validate numerical simulations of flow and pressure in an abdominal aortic aneurysm (AAA) using phase-contrast magnetic resonance imaging (PCMRI) and an in vitro phantom under physiological flow and pressure conditions. We constructed a two-outlet physical flow phantom based on patient imaging data of an AAA and developed a physical Windkessel model to use as outlet boundary conditions. We then acquired PCMRI data in the phantom while it operated under conditions mimicking a resting and a light exercise physiological state. Next, we performed in silico numerical simulations and compared experimentally measured velocities, flows, and …