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Biomedical Engineering and Bioengineering Commons™
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Full-Text Articles in Biomedical Engineering and Bioengineering
Fabrication Of Hydroxyapatite-Biodegradable Polymer Scaffolds By Electrospinning For Potential Bone Tissue Application, Satomi Suzuki
Fabrication Of Hydroxyapatite-Biodegradable Polymer Scaffolds By Electrospinning For Potential Bone Tissue Application, Satomi Suzuki
Theses
The purpose of this study is to determine the potential of combining hydroxyapatite (HA) and polymers to form synthetic composite materials used for bone tissue engineering applications. In this study, ceramic-biodegradable polymer composites are fabricated by electrospinning method. The biodegradable polymers used are poly(L-lactic acid) (PLLA), and poly(lactide-co-glycolide) (PLGA). Two types of HA-polymer solutions are first prepared to achieve HA weight percentage of 0, 10, and 25%of the total combined weight of HA and PLLA, and HA and PLGA. The solutions are electrospun to form nanofibrous mats incorporated with HA powder. A biomimetic process was also conducted as a …
Fabrication Of Aligned Nanofiber Yarns, Mats And Isolation Of Single Nanofiber In Electrospinning, Venkatesh T. Nathilvar
Fabrication Of Aligned Nanofiber Yarns, Mats And Isolation Of Single Nanofiber In Electrospinning, Venkatesh T. Nathilvar
Theses
Electrospinning has been extensively used as an effective technique for the fabrication of submicron and nanometer scale polymeric fibers. In spite of technological advances in electrospinning, creating a highly aligned fiber structure is a tough target to be achieved because of the chaotic motion of the electrospinning jet. In this study, two different techniques have been adopted to form a highly aligned nanofibrous scaffolds. Using these methods highly aligned fiber yams and mats are produced from Cellulose Acetate (CA) in a mixed solvent of acetone and water. In both the techniques the nanofibers suspend over the gap in a highly …
Determination Of The Mechanical Properties Of Electrospun Gelatin Based On Polymer Concentration And Fiber Alignment, Leander Taylor Iii
Determination Of The Mechanical Properties Of Electrospun Gelatin Based On Polymer Concentration And Fiber Alignment, Leander Taylor Iii
Theses and Dissertations
The process of electrospinning has given the field of tissue engineering insight into many aspects of tissue engineered scaffolds, including how factors such as fiber diameter and porosity are affected by polymer concentration. However, the affects of fiber alignment upon the material properties of electrospun scaffolds remains unclear. The purpose of this study is to determine how the material properties of electrospun gelatin scaffolds are affected by changes in fiber alignment and starting gelatin concentration. Gelatin scaffolds, with starting concentrations of 80, 100, and 130mg/m1, were electrospun onto a target mandrel rotating at various speeds. Samples of each scaffold were …