Open Access. Powered by Scholars. Published by Universities.®

Biomedical Engineering and Bioengineering Commons

Open Access. Powered by Scholars. Published by Universities.®

1998

Discipline
Institution
Keyword
Publication
Publication Type
File Type

Articles 1 - 30 of 33

Full-Text Articles in Biomedical Engineering and Bioengineering

Model And Clinical Device Development For Noninvasive Diagnosis Of Low Back Pain And Dysfunction, Ravi Patraju Dec 1998

Model And Clinical Device Development For Noninvasive Diagnosis Of Low Back Pain And Dysfunction, Ravi Patraju

Theses

Millions of people suffer from acute or chronic low back pain. In order for proper treatment to be administered, a patient must receive an accurate diagnosis. Therefore, it is critical to develop an objective model to measure the motion and any dysfunction of a patient's low back. Only then can a physician effectively implement the correct therapy and measure its effectiveness through follow-up to minimize or eliminate low back pain.

Numerous cadaveric, active and passive studies have been done to understand the mechanics of low back disorders. However, only living human subjects suffer from low back pain and therefore ...


A Continuous Process For The Conversion Of Vegetable Oils Into Methyl Esters Of Fatty Acids, Hossein Noureddini, D Harkey, V Medikonduru Dec 1998

A Continuous Process For The Conversion Of Vegetable Oils Into Methyl Esters Of Fatty Acids, Hossein Noureddini, D Harkey, V Medikonduru

Papers in Biomaterials

A continuous process for the transesterification of triglycerides to methyl esters was investigated in a pilot plant. The process was equipped with a motionless and a high-shear mixer. The experimental studies explored variations in the mixing intensity, stoichiometry, and catalyst concentration on the overall conversion. The combined as well as individual effect of mixers was examined. The developed process resulted in high conversions of vegetable oils into methyl esters. Conversion of triglycerides to methyl esters in excess of 98% was achieved. Larger excess amounts of alcohol favored higher conversions. The motionless and high-shear mixers each provided adequate mixing for the ...


Multiscale Modeling Of Recrystallization, A. W. Godfrey, E. A. Holm, D. A. Hughes, M. A. Miodownik, Richard Alan Lesar Nov 1998

Multiscale Modeling Of Recrystallization, A. W. Godfrey, E. A. Holm, D. A. Hughes, M. A. Miodownik, Richard Alan Lesar

Richard Alan Lesar

We propose a multi length scale approach to modeling recrystallization which links a dislocation model, a cell growth model and a macroscopic model. Although this methodology and linking framework will be applied to recrystallization, it is also applicable to other types of phase transformations in bulk and layered materials. Critical processes such as the dislocation structure evolution, nucleation, the evolution of crystal orientations into a preferred texture, and grain size evolution all operate at different length scales. In this paper we focus on incorporating experimental measurements of dislocation substructures, misorientation measurements of dislocation boundaries, and dislocation simulations into a mesoscopic ...


Enzymatic Glycerolysis Of Soybean Oil , Hossein Noureddini, S E. Harmeier Oct 1998

Enzymatic Glycerolysis Of Soybean Oil , Hossein Noureddini, S E. Harmeier

Papers in Biomaterials

Enzymatic glycerolysis of soybean oil was studied. Of the nine lipases that were tested in the initial screening, Pseudomonas sp. resulted in the highest yield of monoglycerides. Lipase from Pseudomonas sp. was further studied for the influence of temperature, thermal stability, enzyme/oil ratio, and glycerol/oil ratio. A full factorial optimization approach was performed. The following conditions were tested over the specified ranges: temperature (30?70°C), thermal stability (30?70°C), enzyme/oil ratio (0.05?0.2 g enzyme/10 g oil), glycerol/oil ratio (1:1?3:1 glycerol/oil molar ratio) and 1 h reaction ...


Method For Improving Consolidation Of Powder Resin, David A. Pienkowski, Eric A. Grulke, Robert J. Jacob Sep 1998

Method For Improving Consolidation Of Powder Resin, David A. Pienkowski, Eric A. Grulke, Robert J. Jacob

Biomedical Engineering Faculty Patents

A method for improving consolidation of powder resin is provided. The method broadly includes the steps of: (1) sorting particles of the powder resin according to their diameter; (2) combining the sorted particles having a first diameter D1 with the sorted particles having a second diameter D2 so as to form a particle mixture; (3) applying a vibration to the particle mixture; (4) heating the particle mixture; and (5) delivering the particle mixture through a nozzle or into a mold. The particle diameters D1 and D2 are chosen so that once combined there is optimal close packing of the three-dimensional ...


Analysis Of Multi-Lead Qt Dispersion By Means Of An Algorithm Implemented On Labview, Zafer Sahinoglu Aug 1998

Analysis Of Multi-Lead Qt Dispersion By Means Of An Algorithm Implemented On Labview, Zafer Sahinoglu

Theses

QT dispersion measurement is significant in diagnostic ECG, and several methods are proposed in the literature to implement QT measurement.

This study consists of two parts: The first part was the development of an algorithm to measure both QT interval and QT dispersion. To check the reliability of the algorithm, 25 single channel ECGs were recorded and their QT intervals were computed. On two subjects, three and four lead ECG data were recorded respectively and their QT dispersions were statistically analyzed. Another part of this study dealt with the effect of the electric dipole of the heart on QT dispersion ...


Measurement Of The Baroreceptor Sensitivity Index (Brsi) In The Frequency Domains, Tanvir Raquib Aug 1998

Measurement Of The Baroreceptor Sensitivity Index (Brsi) In The Frequency Domains, Tanvir Raquib

Theses

Time domain analysis for calculating the Baroreceptor Sensitivity Index (BRSI) did not always provide an accurate result. It also had another limitation in that it could not show the influence of the autonomic nervous system for different subjects. The correlation coefficient is a mechanism that was used to either accept or reject the BRSI values in the time domain but the correlation coefficient values changed drastically depending on how many sample points were selected for the calculation.

On the other hand, frequency domain analysis for the BRSI calculation was relatively easier and provided more accurate information compared to the time ...


Runoff And Erosion Following Field Application Of Beef Cattle Manure And Compost, John E. Gilley, Bahman Eghball Jul 1998

Runoff And Erosion Following Field Application Of Beef Cattle Manure And Compost, John E. Gilley, Bahman Eghball

Biological Systems Engineering: Papers and Publications

Manure or compost from beef cattle feedlots can be excellent sources of nutrients and organic matter when added to soils. This study was conducted to determine the effect of a single application of manure and compost on runoff and erosion under no-till and tillage conditions. Tillage consisted of a single disking operation up and down the slope on a Sharpsburg soil which was cropped to grain sorghum or wheat the previous season. Manure and compost were applied at rates required to meet corn fertility requirements. Additional experimental treatments included the application of inorganic fertilizer and an untreated check. The addition ...


Development Of A Practical And Effective Technique To Determine The Complete Level Of Autonomic Neural Activity During Stress, Vikki Hazelwood May 1998

Development Of A Practical And Effective Technique To Determine The Complete Level Of Autonomic Neural Activity During Stress, Vikki Hazelwood

Theses

Clinical evidence exists to suggest that an individual's level of stress contributes to the state of many physiological and psychological disorders, The autonomic nervous system, by adjusting parasympathetic and sympathetic activity, is attributed with the control over an individual's level of neural stress. Therefore, it is desired to develop a better and quantitative understanding of the stress! autonomic system mechanism.

Previous work has been done to gain a partial understanding of such activity. The primary objective for this study is to complement and advance the previous work by determining whether there is other physiological data which could reveal ...


Mathematical Model Of Human Sit-To-Stand And Stand-To-Sit Motion Analysis, Jayeshkumar Gandhi May 1998

Mathematical Model Of Human Sit-To-Stand And Stand-To-Sit Motion Analysis, Jayeshkumar Gandhi

Theses

In designing a device for an amputee, it is important to find those underlying principles which determine the normal human sit-to-stand task. For this purpose we have developed a mathematical model of human sit-to-stand movement, which it is possible to predict the minimum mechanical energy consumption to move from the sit-to-stand position.

To the best of author's knowledge, this thesis represents the first time that the periodic motion of stand-to-sit and sit-to-stand movements have been mathematically modeled by a simple mechanical system. A complex model, such as the one used by Seireg and Arvikar (1973) [1] that contained 31 ...


Quantitative Estimation Of Heparin Content On Biological Pericadium Tissue Using In Vitro Anti-Factor Xa Assay, Jean-Claude Simeon May 1998

Quantitative Estimation Of Heparin Content On Biological Pericadium Tissue Using In Vitro Anti-Factor Xa Assay, Jean-Claude Simeon

Theses

Shelhigh Inc. (Millburn, NJ) has developed a new heparin binding technique to biological tissues. The technique seems to bind heparin to tissues in a more permanent fashion. Shelhigh's heparinized biological tissues are intended for use in long term implants. This investigation was undertaken to assess whether heparin leaching is prevalent when tissues are quarantine for long shelflife at room temperature, whether tissues maintained thromboresistance properties when in contact with plasma and to estimate heparin content of the tissues.

The study used anti-factor Xa assaying methods: clotting time and chromogenic factor Xa sensitive substrate in order to fulfill the aforementioned ...


Quantification Of Mitral Regurgitation With Mr Phase-Velocity Mapping Using A Control Volume Method, George P. Chatzimavroudis, John N. Oshinski, Roderic I. Pettigrew, Peter G. Walker, Robert H. Franch, Ajit P. Yoganathan May 1998

Quantification Of Mitral Regurgitation With Mr Phase-Velocity Mapping Using A Control Volume Method, George P. Chatzimavroudis, John N. Oshinski, Roderic I. Pettigrew, Peter G. Walker, Robert H. Franch, Ajit P. Yoganathan

Chemical & Biomedical Engineering Faculty Publications

Reliable diagnosis and quantification of mitral regurgitation are important for patient management and for optimizing the time for surgery. Previous methods have often provided suboptimal results. The aim of this in vitro study was to evaluate MR phase-velocity mapping in quantifying the mitral regurgitant volume (MRV) using a control volume (CV) method. A number of contiguous slices were acquired with all three velocity components measured. A CV was then selected, encompassing the regurgitant orifice. Mass conservation dictates that the net inflow into the CV should be equal to the regurgitant flow. Results showed that a CV, the boundary voxels of ...


Local Mechanical Spectroscopy With Nanometer-Scale Lateral Resolution, Nancy Burnham, F Oulevey, G Gremaud, A Semoroz, Aj Kulik, E Dupas, D Gourdon Apr 1998

Local Mechanical Spectroscopy With Nanometer-Scale Lateral Resolution, Nancy Burnham, F Oulevey, G Gremaud, A Semoroz, Aj Kulik, E Dupas, D Gourdon

Nancy A. Burnham

A new technique has been developed to probe the viscoelastic and anelastic properties of submicron phases of inhomogeneous materials. The measurement gives information related to the internal friction and to the variations of the dynamic modulus of nanometer-sized volumes. It is then the nanoscale equivalent to mechanical spectroscopy, a well-known macroscopic technique for materials studies, also sometimes called dynamic mechanical (thermal) analysis. The technique is based on a scanning force microscope, using the principle of scanning local-acceleration microscopy (SLAM), and allows the sample temperature to be changed. It is called variable-temperature SLAM, abbreviated T-SLAM. According to a recent proposition to ...


Multidirectional Ecg Coherent Optimal Timing Of Defibrillation Shocks, Abhijit R. Patwardhan, Fabio M. Leonelli Apr 1998

Multidirectional Ecg Coherent Optimal Timing Of Defibrillation Shocks, Abhijit R. Patwardhan, Fabio M. Leonelli

Biomedical Engineering Faculty Patents

A method for of delivering a defibrillation shock to a heart at an optimal time to stop ventricular fibrillation which involves obtaining an electrocardiogram of a heart in at least two directions, determining a time-coherency of the electrocardiogram based upon each of the at least two directions, and computing a tracking function from the time-coherency. An optimal time to apply a defibrillation shock to the heart is determined by locating a local maximum on the tracking function. The method utilizes spacia characteristics of the ventricular fibrillation. The method can be incorporated into implantable cardioverter defibrillators utilizing existing hardware technology.


Friction Anisotropy And Asymmetry Of A Compliant Monolayer Induced By A Small Molecular Tilt, Nancy Burnham, M Liley, D. Gourdon, Dimitrios Stamou, U Meseth, T Fischer, C Lautz, H Stahlberg, H Vogel, C Duschl Apr 1998

Friction Anisotropy And Asymmetry Of A Compliant Monolayer Induced By A Small Molecular Tilt, Nancy Burnham, M Liley, D. Gourdon, Dimitrios Stamou, U Meseth, T Fischer, C Lautz, H Stahlberg, H Vogel, C Duschl

Nancy A. Burnham

Lateral force microscopy in the wearless regime was used to study the friction behavior of a lipid monolayer on mica. In the monolayer, condensed domains with long-range orientational order of the lipid molecules were present. The domains revealed unexpectedly strong friction anisotropies and non-negligible friction asymmetries. The angular dependency of these effects correlated well with the tilt direction of the alkyl chains of the monolayer, as determined by electron diffraction and Brewster angle microscopy. The molecular tilt causing these frictional effects was less than 15 degrees, demonstrating that even small molecular tilts can make a major contribution to friction.


Automated Docking Of Α-(1,4)- And Α-(1,6)-Linked Glucosyl Trisaccharides In The Glucoamylase Active Site, Pedro M. Coutinho, Michael K. Dowd, Peter J. Reilly Mar 1998

Automated Docking Of Α-(1,4)- And Α-(1,6)-Linked Glucosyl Trisaccharides In The Glucoamylase Active Site, Pedro M. Coutinho, Michael K. Dowd, Peter J. Reilly

Chemical and Biological Engineering Publications

Low-energy conformers of five α-(1,4)- and α-(1,6)-linked glucosyl trisaccharides were flexibly docked into the glucoamylase active site using AutoDock 2.2. To ensure that all significant conformational space was searched, the starting trisaccharide conformers for docking were all possible combinations of the corresponding disaccharide low-energy conformers. All docked trisaccharides occupied subsites −1 and +1 in very similar modes to those of corresponding nonreducing-end disaccharides. For linear substrates, full binding at subsite +2 occurred only when the substrate reducing end was α-(1,4)-linked, with hydrogen-bonding with the hydroxymethyl group being the only polar interaction ...


Method For Reducing The Generation Of Wear Particulates From An Implant, David A. Pienkowski, Kwon-Yong Lee Jan 1998

Method For Reducing The Generation Of Wear Particulates From An Implant, David A. Pienkowski, Kwon-Yong Lee

Biomedical Engineering Faculty Patents

A method is provided for reducing the amount of wear particulates generated by a total joint orthopaedic implant. The implant consists of two matched articulating components wherein at least one of the components is made of polymer or other material with similar physical properties. The method includes the steps of placing the total joint orthopaedic implant in a fluid bath and articulating the implant in the fluid bath for at least 1,000 cycles. The articulation may be performed in three stages. In the first, the implant is articulated under a load of substantially 0.1-500 Newtons with sliding speeds ...


Current Concepts Review - Corrosion Of Metal Orthopaedic Implants, Joshua J. Jacobs, Jeremy L. Gilbert, Robert M. Urban Jan 1998

Current Concepts Review - Corrosion Of Metal Orthopaedic Implants, Joshua J. Jacobs, Jeremy L. Gilbert, Robert M. Urban

Biomedical and Chemical Engineering

No abstract provided.


College Obtains Confocal Microscope, Julie Schneider Jan 1998

College Obtains Confocal Microscope, Julie Schneider

Iowa State University Veterinarian

Iowa State University recently acquired a Laser Scanning Confocal Microscope. The microscope is located at 1082 Veterinary Medicine in the Image Analysis facility. Confocal microscopy is an improvement over conventional light and fluorescence microscopy in that a finely focused laser beam that rapidly scans the specimen at a single depth illuminates the specimen. Only a thin plane is illuminated within the object, and objects outside of the plane have little effect on the quality of the image. The result is a crisp, blur-free image. Images from optical sections taken at different depths can be stored in a computer and used ...


Production Of Ethers Of Glycerol From Crude Glycerol - The By-Product Of Biodlesel Production, Hossein Noureddini, W R. Dailey, B A. Hunt Jan 1998

Production Of Ethers Of Glycerol From Crude Glycerol - The By-Product Of Biodlesel Production, Hossein Noureddini, W R. Dailey, B A. Hunt

Papers in Biomaterials

Methyl esters of fatty acids (also known as biodiesel), made from the transesterification of vegetable oils and animal fats with methanol, have shown a lot of promise as alternative diesel fuels. Glycerol is the inevitable byproduct of the trans-esterification process. While there are existing markets for glycerol, a significant increase in availability of glycerol, re-sulting from the expanded use of vegetable oils and animal fats, would destabilize the glycerol market. Direct addition of glycerol to the fuel is not possible, however, derivatives of glycerol such as ethers have potential for use as additives with biodiesel, diesel or biodiesel-diesel blends. In ...


Biodiesel Fuel From Animal Fat. Ancillary Studies On Transesterification Of Beef Tallow, Fangrui Ma, L. Davis Clements, Milford Hanna Jan 1998

Biodiesel Fuel From Animal Fat. Ancillary Studies On Transesterification Of Beef Tallow, Fangrui Ma, L. Davis Clements, Milford Hanna

Papers from the Nebraska Center for Biotechnology

Transesterification of beef tallow was investigated. The solubility of ethanol in beef tallow was much higher than that of methanol. At 100 °C the solubility of methanol was 19% (w/w). The solubility of ethanol in beef tallow reached 100% (w/w) at about 68 °C. For the distribution of methanol between beef tallow methyl esters (BTME) and glycerol, the percentage of total methanol in the glycerol phase was higher than that in the fatty acid methyl ester (FAME) phase in a simulated system at room temperature. At 65-80 °C, however, the percentage of total methanol in FAME (60% (w ...


Design Of Tapered Augers For Uniform Unloading Particulate Material From Rectangular Cross-Section Containers, M. S. Burr, Michael F. Kocher, David D. Jones Jan 1998

Design Of Tapered Augers For Uniform Unloading Particulate Material From Rectangular Cross-Section Containers, M. S. Burr, Michael F. Kocher, David D. Jones

Biological Systems Engineering: Papers and Publications

The design equation for an auger to provide uniform unloading of particulate material from a container with a rectangular cross-section (Jones and Kocher, 1995) was revised to account for the minimum flighting height that could effectively unload particles with a known average smallest diameter. A minimum flighting height that was about 64% of the average smallest diameter of the particles was experimentally determined to obtain mean slopes of the top surface of the material not significantly different from zero for screened soybeans. A linear taper that best fit the square root curve for the inside diameter of the auger was ...


Cryptococcus Neoformans Chemotyping By Quantitative Analysis Of H-1 Nuclear Magnetic Resonance Spectra Of Glucuronoxylomannans With A Computer-Simulated Artificial Neural Network, Robert Cherniak, Homayoun Valafar, Laura C. Morris, Faramarz Valafar Jan 1998

Cryptococcus Neoformans Chemotyping By Quantitative Analysis Of H-1 Nuclear Magnetic Resonance Spectra Of Glucuronoxylomannans With A Computer-Simulated Artificial Neural Network, Robert Cherniak, Homayoun Valafar, Laura C. Morris, Faramarz Valafar

Faculty Publications

The complete assignment of the proton chemical shifts obtained by nuclear magnetic resonance (NMR) spectroscopy of de-O-acetylated glucuronoxylomannans (GXMs) from Cryptococcus neoformanspermitted the high-resolution determination of the total structure of any GXM. Six structural motifs based on an α-(1→3)-mannotriose substituted with variable quantities of 2-O-β- and 4-O-β-xylopyranosyl and 2-O-β-glucopyranosyluronic acid were identified. The chemical shifts of only the anomeric protons of the mannosyl residues served as structure reporter groups (SRG) for the identification and quantitation of the six triads present in any GXM. The assigned protons for the mannosyl residues ...


The Effects Of Physiological Levels Of Intermittent Pressure On The Development Of Articular Cartilage In Vitro , Scott Edward Carver Jan 1998

The Effects Of Physiological Levels Of Intermittent Pressure On The Development Of Articular Cartilage In Vitro , Scott Edward Carver

Retrospective Theses and Dissertations

A semi-continuous perfusion system has been designed and constructed to deliver physiological levels of hydrostatic pressure to regenerating cell/polymer constructs of articular cartilage over the long term (weeks to months). Prior to being transferred to the pressurized system, equine articular chondrocytes were dynamically seeded onto nonwoven meshes of polyglycolic acid which provide the cells with a three-dimensional growth environment similar to that found in vivo. When applied in an intermittent manner, physiological pressurization at 500 psi was found to stimulate articular chondrocytes to produce regenerated constructs with greater concentrations of sulfated glycosaminoglycan compared to control (unpressurized) constructs, while the ...


Relationships Among Grain Sorghum Quality Factors, Roberto A. Buffo, Curtis L. Weller, Anne M. Parkhurst Jan 1998

Relationships Among Grain Sorghum Quality Factors, Roberto A. Buffo, Curtis L. Weller, Anne M. Parkhurst

Biological Systems Engineering: Papers and Publications

Correlations among grain sorghum quality factors (proximate composition, physical properties, and water absorption properties) were evaluated. Samples of 46 commercial hybrids (24 and 22 from crop years 1993 and 1994) were analyzed for starch, protein, crude free fat, test weight, absolute density, 1,000 kernel weight, percent kernel abraded, water absorption index, initial water absorption rate, and moisture saturation point. Test weight, absolute density, and percent kernel abraded were positively correlated among themselves (r > 0.5). Protein was negatively correlated with both test weight and absolute density (r < -0.5), while moisture saturation point showed negative correlations with test weight, absolute density, 1,000 kernel weight, and percent kernel abraded (r < -0.4). Principal component factor analysis through the covariance matrix explained 95% of the total variation of quality factors among hybrids (two factors), and, through the correlation matrix, 85% of the total variation (five factors). Water absorption rate decreased with increasing starch content of grain sorghum kernels as water absorption rate increased and amount of water for saturation decreased with softening of kernels.


Opto-Electronic Sensor System For Rapid Evaluation Of Planter Seed Spacing Uniformity, Michael F. Kocher, Yubin Lan, Changhe Chen, John A. Smith Jan 1998

Opto-Electronic Sensor System For Rapid Evaluation Of Planter Seed Spacing Uniformity, Michael F. Kocher, Yubin Lan, Changhe Chen, John A. Smith

Biological Systems Engineering: Papers and Publications

An opto-electronic seed spacing evaluation system that measured time intervals between seeds and detected front-to-back location of seed drop events relative to the planter was used to rapidly determine planter seed spacing uniformity in the laboratory. The seed detection sensor for the opto-electronic system consisted of a rectangular photogate with 24 phototransistors receiving light beams from 24 LEDs opposite to them. The system also included circuitry to interface the photogate with a digital I/O board in a personal computer. The opto-electronic system was tested with three planter configurations. During the tests, the photogate was positioned beneath the seed drop ...


Gamma-Ray Imaging Detector For Small Animal Research, Andrew Gerard Weisenberger Jan 1998

Gamma-Ray Imaging Detector For Small Animal Research, Andrew Gerard Weisenberger

Dissertations, Theses, and Masters Projects

A novel radiation imaging technology for in vivo molecular imaging in small mammals is described. The goal of this project is to develop a new type of imaging detector system suitable for real-time in vivo probe imaging studies in small animals. This technology takes advantage of the gamma-ray and x-ray emission properties of the radioisotope iodine 125 (125I) which is employed as the label for molecular probes. The radioisotope 125I is a gamma-ray emitting radioisotope that can be commercially obtained already attached to biomedically interesting molecules to be used as tracers for biomedical and molecular biology research.;The isotope 125I ...


Controlled Environment Potentiostat To Study Solid-Aqueous Systems, R A. Petrie, P. R. Grossl, Ronald C. Sims Jan 1998

Controlled Environment Potentiostat To Study Solid-Aqueous Systems, R A. Petrie, P. R. Grossl, Ronald C. Sims

Biological Engineering Faculty Publications

We designed a redox apparatus that controls electropotenial (Eh), pH, and temperature. The apparatus is fully automated and can be assembled from equipment found in most soil analytical laboratories. The reactor can maintain environmental conditions used to evaluate the chemical fate of contaminants under natural conditions (natural attenuation) or adjust them to a new steady state to evaluate the effect of engineered remediation on a subsurface system. It can operate within a wide range of redox potential values (−400 to 400 mV) and at any pH value. The stability and accuracy of the instrument was tested by performing Eh-pH titrations ...


Sensory Changes In Adults With Unilateral Transtibial Amputation, Judith B. Kosasih, Barbara Silver-Thorn Jan 1998

Sensory Changes In Adults With Unilateral Transtibial Amputation, Judith B. Kosasih, Barbara Silver-Thorn

Biomedical Engineering Faculty Research and Publications

The purpose of this study was to describe the sensory changes in adults with unilateral transtibial amputation

(TTA), as any loss of sensation may have significant impact on the successful use of a prosthesis. Sensory modalities of light touch, deep pressure, vibration, and superficial pain (pinprick) were examined on the residual and contralateral limbs of 16 veterans with TTA. Six subjects demonstrated normal sensation on the contralateral limb and impaired sensation of superficial pain, vibration, and/or light touch on the residual limb. Superficial pain was the most frequently impaired sensation, and vibration and superficial pain sensation appeared to be ...


Development Of A Multiple-Lumen Nerve Cuff Utilizing Growth Stimulant Patterns For Controlled Regeneration , Yueh-Sheng Chen Jan 1998

Development Of A Multiple-Lumen Nerve Cuff Utilizing Growth Stimulant Patterns For Controlled Regeneration , Yueh-Sheng Chen

Retrospective Theses and Dissertations

Silicone rubber multiple-lumen nerve cuffs were used to compare the effectiveness of two varieties of nerve growth stimulants (collagen and a mixture of collagen, fibronectin, and laminin) at the same time for regenerating cables across the same gap. The right sciatic nerve was transected in adult Sprague-Dawley rats. The proximal and distal stumps were inserted each into an end of the single lumen portion of a multiple-lumen cuff in which different chemical fillings were used in 6 tubes of the multiple lumen portion of the cuff. The filling pattern alternated with collagen gel or with a gel mixture of collagen ...