Biomedical Engineering and Bioengineering Commons^™

Using Kriging To Interpolate Spatially Distributed Volumetric Medical Data, Stephen M. Matechik

Theses and Dissertations

Routine cases in diagnostic radiology require the interpolation of volumetric medical imaging data sets. Inaccurate renditions of interpolated volumes can lead to the misdiagnosis of a patient's condition. It is therefore essential that interpolated modality space estimates accurately portray patient space. Kriging is investigated in this research to interpolate medical imaging volumes. Kriging requires data to be spatially distributed. Therefore, magnetic resonance imaging (MRI) data is shown to exhibit spatially regionalized characteristics such that it can be modeled using regionalized variables and subsequently be interpolated using kriging. A comprehensive, automated, three-dimensional structural analysis of the MRI data is accomplished to …

Pulse Coupled Neural Networks For The Segmentation Of Magnetic Resonance Brain Images, Shane L. Abrahamson

Theses and Dissertations

This research develops an automated method for segmenting Magnetic Resonance (MR) brain images based on Pulse Coupled Neural Networks (PCNN). MR brain image segmentation has proven difficult, primarily due to scanning artifacts such as interscan and intrascan intensity inhomogeneities. The method developed and presented here uses a PCNN to both filter and segment MR brain images. The technique begins by preprocessing images with a PCNN filter to reduce scanning artifacts. Images are then contrast enhanced via histogram equalization. Finally, a PCNN is used to segment the images to arrive at the final result. Modifications to the original PCNN model are …

Evaluation Of Segmentation For Bone Structures In 3d Rendering Of Ultrasound Residual Limb Images, Min C. Baker

Theses and Dissertations

Prosthetists today widely practice manual socket fitting, which produces subjective, inconsistent results. To address this problem, the Computerized Anthropometry Research and Design (CARD) Laboratory is developing a computer-aided socket design system that acquires ultrasound datasets of an amputee's residual limb, creates a 3D model, and helps identify load- bearing and pressure-relief areas. This research project focuses on providing 3D visualization of a residual limb to support the CARD Laboratory's efforts. Creating the 3D model of the skin and two bone contours requires two major steps: segmentation to identify the objects of interest and a surface tracking algorithm to generate the …

Clustered Microcalcification Detection Using Optimized Difference Of Gaussians, Edward M. Ochoa

Theses and Dissertations

The objective of this thesis is to design an automated microcalcification detection system to be used as an aid in radiologic mammogram interpretation. This research proposes the following methodology for clustered microcalcification detection. First, preprocess the digitized film mammogram to reduce digitization noise. Second, spatially filter the image with a difference of Gaussians (DoG) kernel. To detect potential microcalcifications, segment the filtered image using global and local thresholding. Next, cluster and index these detections into regions of interest (ROIs). Identify ROIs on the digitized image (or hardcopy printout) for final radiologic diagnosis.

A New Device For Performing Simultaneous Sterno-Thoracic Cardiopulmonary Resuscitation (Sst-Cpr), Deepak S. Gupta

Theses and Dissertations

There are two different physiological mechanisms that cause blood to circulate around the human body during cardiopulmonary resuscitation. The "cardiac pump" generates blood flow by squeezing blood out of the heart as the sternum is depressed. The "thoracic pump" generates flow by forcing blood out of the heart and the great vessels as the intrathoracic pressure rises due to chest compression.

To date, all CPR techniques try to circulate blood during cardiac arrest by exploiting elite; the cardiac pump or the thoracic pump mechanism of blood flow. No mechanical CPR device thus far invented has tried to exploit both mechanisms …