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Full-Text Articles in Biomedical Engineering and Bioengineering
A Novel Intervention To Prevent Post-Traumatic Osteoarthritis Following Knee Joint Injury, Gerardo E. Narez
A Novel Intervention To Prevent Post-Traumatic Osteoarthritis Following Knee Joint Injury, Gerardo E. Narez
Doctoral Dissertations
The knee joint is the most commonly injured body part in the human body. Injuries as a result of participation in sports, or other recreational activities, often leads to damage to the anterior cruciate ligament (ACL) and meniscus. Injury to these tissues is strongly associated with subsequent knee post-traumatic osteoarthritis (PTOA), which is considered a serious disease because it greatly impacts a patient’s quality of life and significantly increases their risk of premature death. To return stability to the joint, the current clinical treatment is to perform reconstruction of the torn ACL and a meniscal debridement, or meniscectomy, when needed. …
Mechanical Interventions In Soft Tissue Repair, Elizabeth Marie Meier
Mechanical Interventions In Soft Tissue Repair, Elizabeth Marie Meier
Wayne State University Dissertations
This body of work sets to investigate some of these mechanical interventions that are designed to promote wound healing, repair, or even replace an injured tissue. By investigating three separate tissues and three separate mechanical interventions, we can draw conclusions about the implications of including mechanical interventions in biomedical research and clinical treatments. The use of sutures to close wounds is highly common, however the effects of sutures on the tensile mechanics of human skin are largely unknown. To evaluate how sutures may affect uniaxial tensile mechanics, human skin samples were sutured and loaded in tension in multiple orientations. The …
Bi-Directional Fatigue Life Behavior Of Bovine Meniscus, Jaremy Creechley
Bi-Directional Fatigue Life Behavior Of Bovine Meniscus, Jaremy Creechley
Boise State University Theses and Dissertations
Meniscal injuries due to tissue tearing are prevalent in the U.S. yet the failure behavior of the meniscus is poorly understood. Clinical studies indicate that fatigue failure causes many of these tears. The highly circumferentially aligned fibers result in transversely isotropic material properties. Tears preferentially align bi-directionally to the fiber orientation. The aim of this study is to present the bi-directional fatigue life behavior of meniscal fibrocartilage. A novel fatigue life approach was developed to achieve this aim. Forty-eight bovine specimens were subjected to cyclic sinusoidal tension-tension stress at 2 Hz until rupture. Normalized peak tensile stresses were determined at …
Finite Element Analysis Of The Effect Of Low-Speed Rear End Collisions On The Medial Meniscus, Daniel J. Tichon
Finite Element Analysis Of The Effect Of Low-Speed Rear End Collisions On The Medial Meniscus, Daniel J. Tichon
Master's Theses
Low-speed, rear end vehicle collisions can inflict soft tissue damage to the passenger’s knees, especially the medial meniscus, which has been previously unexplained in published literature. It is difficult to determine if factors such as age or other injury was the primary cause of the injury or if the accident acutely caused the meniscal tear. Rear end collisions may produce a combination of compressive loading and torque about the knee that will injure the medial meniscus during the initial impact and the rebound phase. The purpose of this study is to determine if it is possible for rear end low-speed …