Biomedical Engineering and Bioengineering Commons^™

Eeg Classifier Validation Methods For Neuroprosthetic Hand Development, Keigo Yamauchi

USF Tampa Graduate Theses and Dissertations

To date, many challenges have been reported in the development of neuroprosthetic hands using EEG and neural signals. In this study, we report the results of a literature review on Brain Computer Interface (BCI) technology, an investigation of estimation methods using applications in MATLAB, and the results of Electroencephalography (EEG) classification to assist in the development of neural prosthetic hands using biological signals such as EEG. Confusion Matrix was created using Motor Imagery (MI) data as the predictive value, and the average accuracy of more than 90% was obtained for the K-Nearest Neighbor (KNN) and decision tree method. The results …

Computational Modeling Of 3d-Printed Lactobacillus-Antibiotic Scaffolds For Bacterial Vaginosis., Veeresh P. Rai

Electronic Theses and Dissertations

The standard treatment for bacterial vaginosis (BV) is currently antibiotics, such as metronidazole, clindamycin, or tinidazole. These antibiotics are highly effective in getting rid of bacteria in the female reproductive tract (FRT); however, there are some bacteria that provide benefits to the FRT which also get expunged. While there are many strains of bacteria that play a beneficial role in the FRT, lactobacilli are among the most important. These bacteria are responsible for maintaining a healthy environment in the FRT via pH regulation by lactic acid metabolism. Antibiotics eliminate all bacteria from an environment, including lactobacilli, and as a result, …

From Branches To Fibers - Investigating F-Actin Networks With Biochemistry And Mathematical Modeling, Melissa A. Riddle

Senior Honors Projects, 2020-current

F-actin networks have different structures throughout the cell depending on their location or mechanical role. For example, at the leading edge of a migrating cell, F-actin is organized in a region called the lamellipodia as a branched network responsible for pushing the membrane outwards. Behind the lamellipodia is a lamellar actin network where focal adhesions and stress fibers originate, and then within the cell cortex, actin is arranged in a gel-like network. Stress fibers are an important organization of F-actin and how they arise from either the branched lamellipodia network or the gel-like cortex network is poorly understood. Our approach …

A Comparison Of Neural Activity For Peripersonal And Extrapersonal Viewing In Real And Virtual Environments, Olivia Eustice

Honors Theses

This study involved a series of tests comparing the similarities and differences in neural activity at a subject’s peripheral and extrapersonal space in the real environment and virtual reality. We hypothesized that there would be similar brain activity at each of these environments depending on the focal distance of an object from the participant. Peripheral space is the visual space that is a reachable distance from a person. It has an overall neural pattern in the dorsal stream of the brain. Extrapersonal space is the visual space that does not directly surround a person and cannot be directly acted on. …

A Bioinstrumentation Active Learning Educational Module: The Design Of A Working Temperature Sensor Using A Ntc Thermistor, Baylor Bush

Biomedical Engineering Undergraduate Honors Theses

The Department of Biomedical Engineering at the University of Arkansas has continued to develop over the years, with more students enrolling in the program each year. Within the first biomedical engineering course, Introduction to Biomedical Engineering, various topics are introduced to students, and the topic of bioinstrumentation has been one of the most complex and difficult topics for students to comprehend through just a few lectures. In order to aid students in grasping these intricate concepts, an active learning module was developed in which students can work in groups to build a simple thermistor circuit as a temperature sensor. The …

Anxiolytic Effects Of Propranolol And Diphenoxylate On Mice And Automated Stretch-Attend Posture Analysis, Kevin Scott Holly

Doctoral Dissertations

The prevention of social anxiety, performance anxiety, and social phobia via the combination of two generic drugs, diphenoxylate HC1 (opioid) plus atropine sulfate (anticholinergic) and propranolol HCl (beta blocker) was evaluated in mice through behavioral studies. A patent published on a September 8, 2011 by Benjamin D. Holly, US 2011/0218215 Al, prompted the research. The drug combination of diphenoxylate and atropine plus propranolol could be an immediate treatment for patients suffering from acute phobic and social anxiety disorders. Demonstrating the anxiolytic effects of the treatment on mice would validate a mouse model for neuroscientist to be used to detect the …

Characterization Of Peripheral Lung Lesions By Statistical Image Processing Of Endobronchial Ultrasound Images, Aaron T. Madaris

Browse all Theses and Dissertations

This thesis introduces the concept of implementing greyscale analysis, also known as intensity analysis, on endobronchial ultrasound (EBUS) images for the purposes of diagnosing peripheral lung tumors. The statistical methodology of using greyscale and histogram analysis allows the characterization of lung tissue in EBUS images. Regions of interest (ROI) will be analyzed in MATLAB and a feature vector will be created. A feature vector of first-order, second-order and histogram greyscale analysis will be created and used for the classification of malignant vs benign peripheral lung tumors. The tools that were implemented were MedCalc for the initial statistical analysis of receiver …

Development Of A Cell Morphological Analysis Tool To Evaluate The Ultrasound Vibrational Effects On Cell Adhesion, Joseph M. Smith

Dissertations, Master's Theses and Master's Reports - Open

Fibroblast encapsulation is a stage of the wound healing process in which the implanted device is separated from the biological environment due to the formation of fibrotic tissue. Uncontrolled adhesion of fibroblasts, called fibrosis, has the ability to inhibit an implanted device’s functionality over its lifetime. Over time, fibroblasts have been shown to cause loosening and failure of bone-anchor implants which could include the possibility of harming the patient. The encapsulating process could also hinder the sensitivity of implanted biosensors operating in the body for continuous monitoring. Unfortunately, the antifouling surfaces which are commonly used on implanted devices to control …

Semi-Automated Dental Cast Analysis Software, Mathew Thomas

Browse all Theses and Dissertations

Dental casts have been used extensively to study almost all aspects of the human dentition. These aspects varied from the study of tooth form and morphology, inheritance and genetics, growth and development, occlusion, arch alignment and crowding to mathematical determination of dental arch form.

The aim of this project was to develop a tool to semi-automate the measurement of dental casts that would be precise, accurate and efficient. Measurements include tooth widths, arch lengths and widths, angle of rotation and crown area for each tooth.

The task was divided into two different parts: first, the development of semi-automatic software to …

Development Of A Mammographic Image Processing Environment Using Matlab, John L. Kelley

Theses and Dissertations

Breast cancer is a disease that accounts for a disturbingly large number of deaths in females each year. Its prevalence is a topic of concern to all of us since it can affect our families, friends, and coworkers. Although mammographic screening is the most effective method currently available for the early detection of breast cancer, it is far from being an infallible procedure. Mammographic reading is error prone, partly because of the complexity of the task and partly because of the variability in human performance. Computers offer high reproducibility, and when used as an adjunct by the radiologist, may improve …