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Full-Text Articles in Biomedical Engineering and Bioengineering
Low-Cost Device For Laser Phacoemulsification: A Preliminary Study, Mitchell Harrah
Low-Cost Device For Laser Phacoemulsification: A Preliminary Study, Mitchell Harrah
USF Tampa Graduate Theses and Dissertations
The current gold standard of cataract removal surgery is phacoemulsification systems. These are divided based on the type of devices used; both are considered equal but with different delivery modes. These delivery methods are either acoustic or light-based. However, these devices pose two hurdles for impoverished areas: high costs and heavy resource usage. This thesis proposes a novel phacoemulsification system is based on the low-cost, off-shelf laser diodes that implement light-based phacoemulsification of cataracts. The system is tested for viability over two methods: finite element analysis and experimentation on various phantoms. Simulations on the device have occurred on the COMSOL …
Mhealth Elisa System For Point-Of-Care, Arsenii Zhdanov
Mhealth Elisa System For Point-Of-Care, Arsenii Zhdanov
USF Tampa Graduate Theses and Dissertations
Enzyme-linked immunosorbent assay (ELISA) is one of the most important technologies for biochemical analysis critical for diagnosis and monitoring of many diseases. Traditional systems for ELISA incubation and reading are expensive and bulky, thus cannot be used at pointof- care or in the field. Here, we design and demonstrate a new miniature mobile phone based system for ELISA. This mHealth system can be used to complete all steps of the assay, including incubation and reading. It can be fabricated at low cost, portable, and can transfer test results via mobile phone. We have designed the sample dispensing system, incubation chamber, …
Concurrent Detection And Isolation Of Cellular And Molecular Biomarkers, Wanfeng Huang
Concurrent Detection And Isolation Of Cellular And Molecular Biomarkers, Wanfeng Huang
Open Access Dissertations
Detection of cancer markers such as protein biomolecules and cancer cells in bodily fluids is of great importance in early diagnosis, prognosis as well as evaluation of therapy efficacy. Numerous devices have been developed for detecting either cellular or molecular targets, however there has not yet been a system that can simultaneously detect both cellular and molecular targets effectively. Molecule and cell-based assays are important because each type of target can tell a different story about the state of the disease and the two types of information can potentially be combined and/or compared for more accurate biological or clinical assessments. …
Foley Catheter Priming Device, Melissa A. Boswell, Landon Davis, Renee Horn, Tyler Grubb, Jason Green
Foley Catheter Priming Device, Melissa A. Boswell, Landon Davis, Renee Horn, Tyler Grubb, Jason Green
Williams Honors College, Honors Research Projects
A lack of a pressure gradient throughout the catheter prevents urine flow from the bladder and through catheter system in a condition referred to as “air-lock.” The purpose of this project was to design a device that could be utilized by person with a catheter faced with the problem of air-lock to restore urine flow and normal functioning of the catheter system. After a prototype was created, the device was put through a series of tests to insure proper functioning, absence of leakage, and durability. The device created can be added in-line with the catheter system, inconspicuously under the user’s …
Designing An Instrument Based On Native Fluorescence To Determine Soil Microbial Content At A Mars Analog Site, Heather D. Smith
Designing An Instrument Based On Native Fluorescence To Determine Soil Microbial Content At A Mars Analog Site, Heather D. Smith
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
For this research project we designed an instrument to detect bacteria via biomolecular fluorescence. We introduce the current understanding of astrobiology, our knowledge of life beyond Earth, and the commonality of Earth life as it pertains to the search for life on Mars. We proposed a novel technique for searching for direct evidence of life on the surface of Mars using fluorescence. We use the arid region of the Mojave Desert as an analog of Mars. Results indicate the fluorescence of the biotic component of desert soils is approximately as strong as the fluorescence of the mineral component. Fluorescence laboratory …