Biomedical Engineering and Bioengineering Commons^™

High Frequency Oscillations In The Epileptic Brain: Accurate Detection, Effect Of Vigilance State, And Sample Size Considerations, Amir Fared Partu Al-Bakri

Theses and Dissertations--Biomedical Engineering

About a third of all epilepsy patients may experience seizures that are resistant to medication. Surgical resection may be an option for some of these patients, but localization of the epileptogenic zone is difficult and expensive. For this process, the seizures must be observed and recorded in a clinical setting over several days. High-frequency oscillations (HFOs) have emerged as a possible biomarker for predicting the epileptogenic zone from a brief interictal recording of brain electrical activity without having to wait for seizures. The broad objective of this dissertation is to devise methods and criteria for accurate detection, sampling and localization …

High Frequency Field Potentials Of The Cerebellar Cortex, Jonathan David Groth

Dissertations

The cerebellum plays a crucial role in motor coordination along with basal ganglia and the motor areas of the cerebral cortex. Both somatosensory and the cerebro-cerebral pathways bring in massive amounts of neural information to the cerebellum. The output of the cerebellar cortex projects to various motor cortices as well as down to the spinal cord to make its contributions to the motor function.

The origin and function of the field potential oscillations in the cerebellum, especially in the high frequencies, have not been explored sufficiently. The primary objective of this study was to investigate the spatio-temporal characteristics of high …