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Biomedical Engineering and Bioengineering Commons

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Full-Text Articles in Biomedical Engineering and Bioengineering

Elastogenic Characterization Of Rat Bm-Msc-Derived Smcs Towards Use In Soft Tissue Engineering, Sahithya Wintrich Jan 2012

Elastogenic Characterization Of Rat Bm-Msc-Derived Smcs Towards Use In Soft Tissue Engineering, Sahithya Wintrich

ETD Archive

No abstract provided.


Micropatterned Electrospun Nanofibrous Substrates As Scaffolds For Engineered Salivary Glands, David Alexander Soscia Jan 2012

Micropatterned Electrospun Nanofibrous Substrates As Scaffolds For Engineered Salivary Glands, David Alexander Soscia

Legacy Theses & Dissertations (2009 - 2024)

The salivary gland is a complex organ exhibiting a branching, 3-dimensional structure made up of acinar (saliva-producing), and ductal (saliva transporting and modifying) epithelial cells. The high surface area of the gland allows it to efficiently provide the mouth with saliva, maintaining oral cleanliness and comfort. Salivary gland hypofunction, a significant clinical problem often caused by the autoimmune disease Sjögren's syndrome or head and neck radiation for cancer patients, affects millions of Americans and is characterized by a loss of function of salivary gland acinar cells. Chronic xerostomia, or dry mouth, arises as a result of salivary gland hypofunction and …