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Biomedical Engineering and Bioengineering Commons™
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Full-Text Articles in Biomedical Engineering and Bioengineering
Continuum Deformation Model For Drug-Eluting Stent (Des) Medical Devices Using Finite Element Analysis (Fea), Solki Lee
Theses and Dissertations
The development of coronary stent medical devices was originally considered as a major advance in the treatment of obstructive cardiovascular disease. The implantation of stent, however, involves clinical adverse effects such as re-narrowing of arterial wall after stenting. Drug-eluting stents (DES) have been developed to prevent such adverse effects by slowly delivering anti-proliferative and/or anti-inflammatory drugs from coating composites of drug-containing polymers. One of the major issues in DES implantation is, however, that the coatings comprised of drug and polymer composite phases are often fractured or delaminated during the deployment of stent, which can lead to more serious clinical complications. …
Density Functional Theory (Dft) Study On The Hydrolysis Behavior Of Degradable Mg/Mg Alloys For Biomedical Applications, Marjan Nezafati
Density Functional Theory (Dft) Study On The Hydrolysis Behavior Of Degradable Mg/Mg Alloys For Biomedical Applications, Marjan Nezafati
Theses and Dissertations
Magnesium-based (Mg and/or Mg alloys) materials possess many advantageous physicochemical/biological characteristics such as good biocompatibility and similarity of the mechanical properties to the human bone tissue, which renders this material a promising candidate for the biomedical and implant applications. One of the most attractive features of Mg-based materials is the degradability in the physiological environment. With the burst of research on the biodegradable materials for the healthcare device applications, Mg and its alloys attracted a strong attention in the bioengineering field in recent years. However, the major limitation of applying Mg-based materials to biomedical applications is the fast degradation/corrosion rate …