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Biomedical Engineering and Bioengineering Commons™
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Full-Text Articles in Biomedical Engineering and Bioengineering
A Novel Method For Determining Acetabular Orientation, Sean Higgins
A Novel Method For Determining Acetabular Orientation, Sean Higgins
Theses and Dissertations
Enhanced knowledge of the acetabulum is of paramount importance in the diagnostic, planning, and execution stages of procedures and treatments targeting the hip joint. The convoluted and highly variable morphology of the structures comprising the bony pelvis make ascertaining measures of the acetabulum challenging. Furthermore, current methods for determining acetabular orientation assume symmetry between the separate halves of the pelvis by utilizing a coordinate system based on bilateral landmarks. The purpose of this study was to determine the three-dimensional orientation of the entire acetabulum. For this research, an improved programmatic method was developed for determining acetabular orientation using three-dimensional data. …
Coupling Of Audio Signals Into Afm Images, Matthew Manning
Coupling Of Audio Signals Into Afm Images, Matthew Manning
Honors Theses
It is well known that Atomic Force Microscopy imaging is capable of yielding high resolution results with of surfaces at the nanoscale. However, despite the device capabilities and vast applications, AFM microscopy is possibly the most prone to the creation of image artifacts. AFM imaging can easily, and is often, corrupted by various external forces. The most obvious and measurable form of external interference is of course the presence of ambient noise. Most AFM manufactures attempt to counter the effects of such noise on the imaging process through use of noise-proof or noise-resistant shields that cover the microscope aperture. Without …
Quantitative, Spatial Imaging Based Measurements To Assess Cellular Health And Oxygenation In A Tissue Engineered Test System, Erik Bland
All Dissertations
Three-dimensional in vitro tissue test systems are employed to examine cell behavior, test responses to drugs and vaccines, and answer basic biological questions. These systems are more physiologically relevant than two-dimensional cell cultures, and are more relevant, easier and less expensive to maintain than animal models. However, methods used to measure cell behavior and viability have been developed specifically for two-dimensional cell cultures or animal models, and are often not optimally translated to three-dimensional in vitro test systems. The purpose of this work was to aid in the development of three-dimensional, spatially controlled in vitro test systems, and to develop …