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Full-Text Articles in Biomedical Engineering and Bioengineering
Organization And Signal Processing Of The Descending Tracts In The Cervical Spinal Cord, Yanmei Tie
Organization And Signal Processing Of The Descending Tracts In The Cervical Spinal Cord, Yanmei Tie
Doctoral Dissertations
This dissertation addresses the research for the development of spinal cord-computer interface (SCCI). The main objective of SCCI is to generate voluntary motor control signals for individuals with spinal cord injury (SCI).
In the neuroscience aspect, organization of the fibers in the descending tracts of the dorsolateral funiculus of the cervical spinal cord was investigated in cats. The spinal cord was penetrated with silicon substrate microelectrodes at 400 μm intervals in the medio-lateral direction at the C5/C6 and C6/C7 segmental borders. The stimulus consisted of a 20 ms train of charge-balanced biphasic pulses at 330 Hz. The evoked activities from …
Characterization Of Mismatch Between Behavioral Stimuli And Frmi Data Using The Kalman Filter, Jason Steffener
Characterization Of Mismatch Between Behavioral Stimuli And Frmi Data Using The Kalman Filter, Jason Steffener
Dissertations
The advance of blood oxygen level dependent function magnetic resonance imaging, (BOLD fMRI), allows researchers to non-invasively investigate the functioning human brain. The BOLD fMRI response to brief stimuli is called the hemodynamic response function (HRF), which can vary across brain regions and across subjects.
Models of the HRF are used to increase sensitivity of statistical maps; however, they often don't account for spatial and temporal variance. Physiological effects, such as learning, fatigue or habituation, introduce mismatch between statistical models and the data. Methods that use minimal a priori information and track time varying signals are able to show the …