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Investigating The Therapeutic Potential Of Salivary Proteins For Oral Diseases, Dusa Vukosavljevic
Investigating The Therapeutic Potential Of Salivary Proteins For Oral Diseases, Dusa Vukosavljevic
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ABSTRACT
Saliva is responsible for the formation of the acquired enamel pellicle (AEP), a protein
integument formed as a result of selective adsorption of salivary proteins to the enamel
surface. The AEP demonstrates an important role for modulating dental erosion as a
result of its physical properties, along with its salivary and exogenous protein
composition (Chapter 2). In addition, individual proteins that comprise the AEP have
important physiological functions. Histatin 5 (H5) has potent antifungal effect against C.
albicans, the yeast responsible for the initiation of oral candidiasis. We designed an in
vitro model and found, for the first time, …