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Full-Text Articles in Biomedical Engineering and Bioengineering
Characterization Of Histological Changes In The Microvasculature Of Rat Skeletal Muscle After Spinal Cord Injury, Sally Lin
Master's Theses (2009 -)
The purpose of this study was to determine whether there are histological changes in the microvasculature of rat skeletal muscle following chronic spinal cord injury both above and below the level of injury. This study is important because microvascular structure likely impacts muscle performance and cardiovascular health. To the best of our knowledge, this is the only study to investigate microvascular structure within rat skeletal muscle after spinal cord injury. We hypothesized structural remodeling would occur in both the myofibers and microvasculature, which would then manifest in differences in myofiber cross sectional area and microvascular diameter, wall thickness, wall to …
Diffusion Tensor Imaging Of The Central Nervous System Following An Injury To The Spinal Cord And Cell Transplant, Michael Jirjis
Diffusion Tensor Imaging Of The Central Nervous System Following An Injury To The Spinal Cord And Cell Transplant, Michael Jirjis
Dissertations (1934 -)
The purpose of this dissertation research was to characterize the use of magnetic resonance diffusion tensor imaging (DTI) as a diagnostic and prognostic tool in understanding the changes that occur throughout the spinal cord and brain following a spinal cord injury (SCI) and following stem cell transplant. The diffusion of water inside the nervous system is dramatically altered around the lesion site following a traumatic SCI. However, following damage to the spinal cord, little is known about the diffusion characteristics away from an injury and even less is understood about DTI's sensitivity to structural changes that occur following regenerative transplant …