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Biomedical Engineering and Bioengineering Commons™
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Full-Text Articles in Biomedical Engineering and Bioengineering
Mutlifunctional Platforms For Gene And Drug Delivery For Cancer Therapy, Jeffery J. Ambrose Jr.
Mutlifunctional Platforms For Gene And Drug Delivery For Cancer Therapy, Jeffery J. Ambrose Jr.
Doctoral Dissertations
The National Cancer Institute and the American Cancer Society estimate that 1.6 million new cancer incidences and over half a million cancer related deaths occur annually [1][2]. Cancer the second most common cause of death in the United States [1], [2]. Although the causes of cancer can vary depending on cell type, all or almost all instances of cancer arise from a mutation or from an abnormal activation of the cellular genes that control cell growth and mitosis [3].
Treatment of a given cancer type depends on the subtype, stage and progression of the cancer. Varieties of cancer therapy include …
Chitosan Paste From Crawfish Shells As A Synthetic Bone Graft Material: Preparation, Characterization And Animal Study, Jerome G. Saltarrelli Jr.
Chitosan Paste From Crawfish Shells As A Synthetic Bone Graft Material: Preparation, Characterization And Animal Study, Jerome G. Saltarrelli Jr.
Doctoral Dissertations
Bone loss associated with musculoskeletal trauma or metabolic diseases often requires bone grafts. Autograft or allograft bones are limited in supply. Therefore, development of synthetic bone graft materials is an active area of research. For several years the biomaterials group at LSUHSC-Shreveport has been investigating the use of chitosan purified from crawfish shells using a process patented by my research advisor, Dr. Debi Mukherjee.
Chitin is a polysaccharide that exists in fungi, exoskeleton of insects and outer shell of crustaceans. It is biocompatible, osteoconductive, antimicrobial, biodegradable, non-toxic, haemostatic, fungicidal, and the second most abundant natural polysaccharide on earth. Removal of …