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Biomedical Devices and Instrumentation

University of New Mexico

Transdermal arterial gasotransmitter sensor (TAGS)

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Full-Text Articles in Biomedical Engineering and Bioengineering

The Development Of An Instrument To Measure Transdermal Hydrogen Sulfide As A Way To Evaluate Microvascular Health In Humans, Benjamin Thomas Matheson Jul 2021

The Development Of An Instrument To Measure Transdermal Hydrogen Sulfide As A Way To Evaluate Microvascular Health In Humans, Benjamin Thomas Matheson

Biomedical Engineering ETDs

Hydrogen sulfide (H2S) is a gasotransmitter critical in maintaining microcirculation homeostasis. Impaired microcirculation occurs in multiple disease states such as peripheral vascular disease, diabetes mellitus (DM), and hypertension. Early detection and identification of patients with DM who are at risk for heart attack, stroke and amputation due to microvascular disease is crucial. Human skin is an accessible vascular bed that provides an opportunity to non-invasively measure H2S, which could be used as a biomarker to evaluate microvascular health.

In this work, a novel H2S gas sensor, called the transdermal arterial gasotransmitter sensor (TAGSTM …