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Full-Text Articles in Biomedical Engineering and Bioengineering

A Concept For Early Cancer Detection And Therapy, Ronald W. Waynant, Ilko K. Ilev, Kunal Mitra Sep 2003

A Concept For Early Cancer Detection And Therapy, Ronald W. Waynant, Ilko K. Ilev, Kunal Mitra

Biomedical Engineering and Sciences Faculty Publications

Early detection and treatment of breast cancer is least costly in terms of dollars, morbidity and mortality. With new early detection x-ray technology, tumors can be found, diagnosed and treated at a much smaller size than is currently possible. This paper proposes the development of a high resolution, high quality imaging system. It is a laser-driven x-ray system with time-gated detection that removes scattering noise in the image and produces resolution on the order of 10 μm. This higher resolution and higher image quality will enable the detection of one or two millimeter tumors hopefully detecting them before metastasis. We …


Short Pulse Laser Propagation Through Tissues, Champak Das, Ashish Trivedi, Kunal Mitra, Tuan Vo-Dinh Jul 2003

Short Pulse Laser Propagation Through Tissues, Champak Das, Ashish Trivedi, Kunal Mitra, Tuan Vo-Dinh

Biomedical Engineering and Sciences Faculty Publications

An experimental and numerical study is performed to analyze short pulse laser propagation through tissue phantoms without and with inhomogeneities/tumors imbedded in it. Short pulse laser probing techniques has distinct advantages over conventional very large pulse width or cw lasers primarily due to the additional information conveyed about the tissue interior by the temporal variation of the observed signal. Both the scattered temporal transmitted and reflected optical signals are measured experimentally using a streak camera for samples irradiated with a short pulse laser source. Parametric study involving different scattering and absorption coefficients of tissue phantoms and inhomogeneities as well as …