Biomedical Engineering and Bioengineering Commons^™

Interpreting Hemoglobin And Water Concentration, Oxygen Saturation, And Scattering Measured In Vivo By Near-Infrared Breast Tomography, Subhadra Srinivasan, Brian W. Pogue, Shudong Jiang, Hamid Dehghani, Christine Kogel, Sandra Soho, Jennifer J. Gibson, Tor D. Tosteson, Steven P. Poplack, Keith D. Paulsen

Dartmouth Scholarship

Near-infrared spectroscopic tomography was used to measure the properties of 24 mammographically normal breasts to quantify whole-breast absorption and scattering spectra and to evaluate which tissue composition characteristics can be determined from these spectra. The absorption spectrum of breast tissue allows quantification of (i) total hemoglobin concentration, (ii) hemoglobin oxygen saturation, and (iii) water concentration, whereas the scattering spectrum provides information about the size and number density of cellular components and structural matrix elements. These property data were tested for correlation to demographic information, including subject age, body mass index, breast size, and radiographic …

Evaluation Of Intra-And Inter-Fraction Motion In Breast Radiotherapy Using Electronic Portal Imaging Cine Loops, Chrison Lee, Edward Yu, Tomas Kron

Oncology Presentations

Parallel tangent breast irradiation is commonly used postbreast conservation surgery for early breast cancer patient without lymph node involvement to improve local disease control. Intra-fractional and inter-fractional variabilities are often presented in daily treatment setup. The present pilot study used Electronic Portal Imaging (EPI) to evaluate intra-and inter-fraction motion in patients undergoing simple breast tangent radiotherapy.

Compact Supercell Method Based On Opposite Parity For Bragg Fibers, Wang Zhi, Ren Guobin, Lou Shuquin, Liang Weijun, Shangping Guo

Electrical & Computer Engineering Faculty Publications

The supercell- based orthonormal basis method is proposed to investigate the modal properties of the Bragg fibers. A square lattice is constructed by the whole Bragg fiber which is considered a supercell, and the periodical dielectric structure of the square lattice is decomposed using periodic functions (cosine). The modal electric field is expanded as the sum of the orthonormal set of Hermite-Gaussian basis functions based on the opposite parity of the transverse electric field. The propagation characteristics of Bragg fibers can be obtained after recasting the wave equation into an eigenvalue system. This method is implemented with very high efficiency …

Clinical Blood Flow Quantification With Segmented K-Space Magnetic Resonance Phase Velocity Mapping, George P. Chatzimavroudis, Haosen Zhang, Sandra S. Halliburton, James R. Moore, Orlando Simonetti, Paulo R. Schvartzman, Arthur E. Stillman, Richard D. White

Chemical & Biomedical Engineering Faculty Publications

To evaluate the accuracy of segmented k-space magnetic resonance phase velocity mapping (PVM) in quantifying aortic blood flow from through-plane velocity measurements.

Two segmented PVM schemes were evaluated, one with seven lines per segment (seg-7) and one with nine lines per segment (seg-9), in twenty patients with cardiovascular disease. A non-segmented (non-seg) PVM acquisition was also performed to provide the reference data.

There was agreement between the aortic flow curves acquired with segmented and non-segmented PVM. The calculated systolic and total flow volume per cycle from the seg-7 and the seg-9 scans correlated and agreed with the flow volumes from …