Biomedical Engineering and Bioengineering Commons^™

Validation Of A Biomechanical Injury And Disease Assessment Platform Applying An Inertial-Based Biosensor And Axis Vector Computation, Wangdo Kim, Emir A. Vela, Sean S. Kohles, Victor Huayamave

Publications

Inertial kinetics and kinematics have substantial influences on human biomechanical function. A new algorithm for Inertial Measurement Unit (IMU)-based motion tracking is presented in this work. The primary aims of this paper are to combine recent developments in improved biosensor technology with mainstream motion-tracking hardware to measure the overall performance of human movement based on joint axis-angle representations of limb rotation. This work describes an alternative approach to representing three-dimensional rotations using a normalized vector around which an identified joint angle defines the overall rotation, rather than a traditional Euler angle approach. Furthermore, IMUs allow for the direct measurement of …

Algal Biofuel: The Future Of Green Jet Fuel In Air Transportation, Rajee Olaganathan

Publications

The aviation industry is one of the major contributors for the greenhouse gases. As air travel has become inevitable in this modern era, and fossil fuel usage is not sustainable, it is essential to produce renewable fuel and commercialize it to reduce the greenhouse gas emissions. In order to produce an alternate aviation biofuel a lot of industrial and academic collaborations have been developed worldwide. The main concern of this collaborative research is to produce aviation biofuel from renewable resources with low environmental impacts, and which is sustainable at an economically viable price. This mini-review briefly discusses the biotechnological approaches …

Application Of Bioinstrumentation In Developing A Pressure Suit For Suborbital Flight, Pedro Llanos, Erik Seedhouse

Publications

This presentation features Embry-Riddle Aeronautical University's U-2 pressure suit. Built to be light and cost-effective, this suit is comfortable, comes in multiple sizes, operates in pressures up to 5 PSID, has an active airflow-based cooling system, and features bio-instrumentation to measure heart rate, breathing rate, skin temperature and other vitals.

A Patient-Specific Model Of The Biomechanics Of Hip Reduction For Neonatal Developmental Dysplasia Of The Hip: Investigation Of Strategies For Low To Severe Grades Of Developmental Dysplasia Of The Hip, Victor Huayamave, Christopher Rose, Sheila Serra, Brendan Jones, Eduardo Divo, Faissal Moslehy, Alain J. Kassab, Charles T. Price

Publications

A physics-based computational model of neonatal Developmental Dysplasia of the Hip (DDH) following treatment with the Pavlik Harness (PV) was developed to obtain muscle force contribution in order to elucidate biomechanical factors influencing the reduction of dislocated hips. Clinical observation suggests that reduction occurs in deep sleep involving passive muscle action. Consequently, a set of five (5) adductor muscles were identified as mediators of reduction using the PV. A Fung/Hill-type model was used to characterize muscle response. Four grades (1–4) of dislocation were considered, with one (1) being a low subluxation and four (4) a severe dislocation. A three-dimensional model …

Differential Effects Of Refractive Blur On Day And Nighttime Driving Performance, Joanne M. Wood, Michael J. Collins, Alex Chaparro, Ralph Marszalek, Trent Carberry, Philippe Lacherez, Byoung Sun Chu

Publications

PURPOSE. To investigate the effect of different levels of refractive blur on real-world driving performance measured under day and nighttime conditions.

METHODS. Participants included 12 visually normal, young adults (mean age = 25.+- 5.2 years) who drove an instrumented research vehicle around a 4 km closed road circuit with three different levels of binocular spherical refractive blur (+0.50 diopter sphere [DS], +1.00 DS, +2.00 DS) compared with a baseline condition. The subjects wore optimal spherocylinder correction and the additional blur lenses were mounted in modified fullfield goggles; the order of testing of the blur conditions was randomized. Driving …

Mechanics Of Hip Dysplasia Reduction In Infants Using The Pavlik Harness: A Physics Based Computational Model, Orlando Ardila, Eduardo Divo, Faissal Moslehy, George Rab, Alain Kassab, Charles Price

Mechanical Engineering - Daytona Beach

Biomechanical factors influencing the reduction of dislocated hips with the Pavlik harness in patients of Developmental Dysplasia of the Hip (DDH) were studied using a three-dimensional computer model simulating hip reduction dynamics in (1) subluxated and (2) fully dislocated hip joints. Five hip adductor muscles were identified as key mediators of DDH prognosis, and the non-dimensional force contribution of each in the direction necessary to achieve concentric hip reductions was determined. Results point to the adductor muscles as mediators of subluxated hip reductions, as their mechanical action is a function of the degree of hip dislocation. For subluxated hips in …

Even Moderate Visual Impairments Degrade Drivers' Ability To See Pedestrians At Night, Joanne M. Wood, Richard A. Tyrell, Alex Chaparro, Ralph P. Marszalek, Trent P. Carberry, Byoung Sun Chu

Publications

PURPOSE. To determine the effect of moderate levels of refractive blur and simulated cataracts on nighttime pedestrian conspicuity in the presence and absence of headlamp glare.

METHODS. The ability to recognize pedestrians at night was measured in 28 young adults (M ¼ 27.6 years) under three visual conditions: normal vision, refractive blur, and simulated cataracts; mean acuity was 20/40 or better in all conditions. Pedestrian recognition distances were recorded while participants drove an instrumented vehicle along a closed road course at night. Pedestrians wore one of three clothing conditions and oncoming headlamps were present for 16 participants and absent for …

Useful Field Of View Predicts Driving In The Presence Of Distracters, Joanne M. Wood, Alex Chaparro, Philippe Lacherez, Louise Hickson

Publications

Purpose. The Useful Field of View (UFOV®) test has been shown to be highly effective in predicting crash risk among older adults. An important question which we examined in this study is whether this association is due to the ability of the UFOV to predict difficulties in attention-demanding driving situations that involve either visual or auditory distracters.

Methods. Participants included 92 community-living adults (mean age 73.6 +- 5.4 years; range 65– 88 years) who completed all three subtests of the UFOV involving assessment of visual processing speed (subtest 1), divided attention (subtest 2), and selective attention (subtest 3); driving safety …

Computational Analysis Of Hybrid Norwood Circulation With Distal Aortic Arch Obstruction And Reverse Blalock-Taussig Shunt, Andres Ceballos, I. Ricardo Argueta-Morales, Eduardo Divo, Ruben Osorio, Christopher A. Caldarone, Alain J. Kassab, William M. Decampli

Mechanical Engineering - Daytona Beach

BACKGROUND: The hemodynamics characteristics of the hybrid Norwood (HN) procedure differ from those of the conventional Norwood and are not fully understood. We present a multi-scale model of HN circulation to understand local hemodynamics and effects of aortic arch stenosis and a reverse Blalock-Taussig shunt (RBTS) on coronary and carotid perfusion. METHODS: Four 3-dimensional models of four HN anatomic variants were developed, with and without 90% distal preductal arch stenosis and with and without a 4-mm RBTS. A lumped parameter model of the circulation was coupled to a local 3-dimensional computational fluid dynamics model. Outputs from the lumped parameter model …

Computational Fluid Dynamics In Congenital Heart Disease, William M. Decampli, I. Ricardo Argueta-Morales, Eduardo Divo, Alain J. Kassab

Mechanical Engineering - Daytona Beach

Computational fluid dynamics has been applied to the design, refinement, and assessment of surgical procedures and medical devices. This tool calculates flow patterns and pressure changes within a virtual model of the cardiovascular system. In the field of paediatric cardiac surgery, computational fluid dynamics is being used to elucidate the optimal approach to staged reconstruction of specific defects and study the haemodynamics of the resulting anatomical configurations after reconstructive or palliative surgery. In this paper, we review the techniques and principal findings of computational fluid dynamics studies as applied to a few representative forms of congenital heart disease.

Left Ventricular Assist Devices: Engineering Design Considerations, Marwan A. Simaan, Eduardo Divo, George Faragallah, Yu Wang

Publications

Patients with end-stage congestive heart failure awaiting heart transplantation often wait long periods of time (300 days or more on the average) before a suitable donor heart becomes available. The medical community has placed increased emphasis on the use of Left Ventricular Assist Devices or LVADs that can substitute for, or enhance, the function of the natural heart while the patient is waiting for the heart transplant (Poirier, 1997; Frazier & Myers, 1999). Essentially, a rotary LVAD is a pump that operates continuously directing blood from the left ventricle into the aorta by avoiding the aortic valve. Generally speaking, the …

Effect Of Simulated Visual Impairment On Nighttime Driving Performance, Joanne Wood, Alex Chaparro, Trent Carberry, Byoung Sun Chu

Publications

Purpose. This study investigated the effects of simulated visual impairment on nighttime driving performance and pedestrian recognition under real-road conditions.

Methods. Closed road nighttime driving performance was measured for 20 young visually normal participants (M = 27.5 +- 6.1 years) under three visual conditions: normal vision, simulated cataracts, and refractive blur that were incorporated in modified goggles. The visual acuity levels for the cataract and blur conditions were matched for each participant. Driving measures included sign recognition, avoidance of low contrast road hazards, time to complete the course, and lane keeping. Pedestrian recognition was measured for pedestrians wearing either black …

The Effect Of Auditory And Visual Distracters On The Useful Field Of View: Implications For The Driving Task, Joanne Wood, Alex Chaparro, Louise Hickson, Nick Thyer, Philippa Carter, Julie Hancock, Adrene Hoe, Ivy Le, Louisa Sahetapy, Floravel Ybarzabal

Publications

PURPOSE. The driving environment is becoming increasingly complex, including both visual and auditory distractions within the in-vehicle and external driving environments. This study was designed to investigate the effect of visual and auditory distractions on a performance measure that has been shown to be related to driving safety, the useful field of view.

METHODS. A laboratory study recorded the useful field of view in 28 young visually normal adults (mean 22.6 +- 2.2 years). The useful field of view was measured in the presence and absence of visual distracters (of the same angular subtense as the target) and with three …

The Effects Of Luminance Boundaries On Color Perception, Richard E. Kronauer, Charles F. Stromeyer Iii, Alex Chaparro

Publications

The luminance and red-green chromatic detection mechanisms respond to, respectively, the sum and difference of the long-wave (L) and middle-wave (M) zone contrast signals. The most-detectable stimulus is not a small patch of luminance drifting grating, as suggested by others, but rather a small, foveal red-green chromatic flash. Even at the smallest test size examined, 2.3' diameter, the red-green mechanism i~s more sensitive than the luminance mechanism, which has profound implication for visual physiology. When a suprathreshold luminance flash (a pedestal) occurs coincidentally with a red-green chromatic flash, detection of color is facilitated ~2-fold, regardless of spot size, as shown …