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Full-Text Articles in Biomedical Engineering and Bioengineering
Engineering Hyaluronic Acid Carbon Nanotube Nanofibers: A Peripheral Nerve Interface To Electrically Stimulate Regeneration, Elisabeth M. Steel
Engineering Hyaluronic Acid Carbon Nanotube Nanofibers: A Peripheral Nerve Interface To Electrically Stimulate Regeneration, Elisabeth M. Steel
Wayne State University Dissertations
Peripheral nerve injuries annually affect hundreds of thousands of people globally. Current treatments like the gold standard autograft and commercially available nerve guide conduits (NGC) are insufficient to repair long gap peripheral nerve injuries. NGCs can aid recovery but lack key microenvironment cues that promote nerve regeneration. We hypothesized that providing topographical, mechanical, and electrical guidance cues through a nanofibrous composite biopolymer would result in improved neuron growth metrics using an in vitro model. We embedded hydrophilic carbon nanotubes (CNT) within hyaluronic acid (HA) nanofibers by electrospinning. The aims of this study were (1) to define the topographical, nanomechanical, and …
Study Of Mri Signal In The Presence Of Discrete Spherical Magnetic Particles, Paul Kokeny
Study Of Mri Signal In The Presence Of Discrete Spherical Magnetic Particles, Paul Kokeny
Wayne State University Dissertations
Simulating signal behavior in Magnetic Resonance imaging (MRI) is often a necessary step in being able to understand how signal relates to certain physiological parameters. One such parameter of interest in the body is magnetic susceptibility since it is related to iron content. The bulk magnetic susceptibility of an object is a property that describes how magnetized it becomes when placed in an external magnetic field. When the bulk susceptibility of an object arises from the presence of discrete magnetic inclusions, the MRI phase signal inside the object can no longer be determined analytically by assuming it has a continuous …
Identification Of Streptococcus Pyogenes Using Raman Spectroscopy, Ehsan Majidi
Identification Of Streptococcus Pyogenes Using Raman Spectroscopy, Ehsan Majidi
Wayne State University Dissertations
Despite the attention that Raman Spectroscopy has gained recently in the area of pathogen identification, the spectra analyses techniques are not well developed. In most scenarios, they rely on expert intervention to detect and assign the peaks of the spectra to specific molecular vibration. Although some investigators have used machine-learning techniques to classify pathogens, these studies are usually limited to a specific application, and the generalization of these techniques is not clear. Also, a wide range of algorithms have been developed for classification problems, however, there is less insight to applying such methods on Raman spectra. Furthermore, analyzing the Raman …